Despite more than a half century of “safe” cardiopulmonary bypass (CPB), the evidence
base surrounding the conduct of anticoagulation therapy for CPB has not been organized …

The use of heparin for anticoagulation has changed the face of cardiac surgery by allowing
a bloodless and motionless surgical field throughout the introduction of cardiopulmonary …

Despite more than a half century of “safe” cardiopulmonary bypass (CPB), the evidence
base surrounding the conduct of anticoagulation for CPB has not been organized into a …

Left ventricular assist devices (LVAD) have revolutionized the management of advanced
heart failure. However, complications rates remain high, among which hemorrhagic and …

Cardiac surgery with cardiopulmonary bypass determines a serious imbalance of the
hemostatic system. The clinical pattern is multifactorial, involving patient-related, drug …

Complex cardiac procedures often require blood transfusion because of surgical bleeding or
coagulopathy. Thrombelastography (TEG) was introduced in our institution to direct …

Background Anticoagulation is critical in patients supported on extracorporeal membrane
oxygenation (ECMO). The appropriate monitoring strategies for heparin remain unclear …

From preoperative medications to intraoperative needs to postoperative
thromboprophylaxis, anticoagulants are encountered throughout the perioperative period …

Objectives: Extracorporeal Life Support (ECLS) risks thrombotic and hemorrhagic
complications. Optimal anti-coagulation monitoring is controversial. We compared …

Nowadays, unfractionated heparin (UFH) use is limited to selected patient groups at high
risk of both bleeding and thrombosis (patients in cardiac surgery, in intensive care unit, and …