Monoligated palladium (0) species, L1Pd (0), have emerged as the most active catalytic
species in the cross-coupling cycle. Today, there are methods available to generate the …

Palladium catalysed cross-couplings reactions have been a dominant method in synthetic
chemistry for decades. Despite this, the role of the solvent is often taken for granted and …

Chemists often use statistical analysis of reaction data with molecular descriptors to identify
structure-reactivity relationships, which can enable prediction and mechanistic …

While the oxidative addition of Ni (I) to aryl iodides has been commonly proposed in catalytic
methods, an in-depth mechanistic understanding of this fundamental process is still lacking …

The use of two or more metal catalysts in a reaction is a powerful synthetic strategy to access
complex targets efficiently and selectively from simple starting materials. While capable of …

The first now-named Stille reaction was published 38 years ago, and the last comprehensive
revision of this catalysis was in 2004. Since then, the knowledge of the different steps of the …

Sulfur‐containing molecules such as thioethers are commonly found in chemical biology,
organic synthesis, and materials chemistry. While many reliable methods have been …

Two limiting mechanisms are possible for oxidative addition of (hetero) aryl (pseudo) halides
at Pd (0): a 3-centered concerted and a nucleophilic displacement mechanism. Until now …

Conventional analytic techniques that measure ensemble averages and static disorder
provide essential knowledge of the reaction mechanisms of organic and organometallic …

The strong electron-donation and the steric bulk of trialkylphosphines renders them as very
useful ligands for palladium-catalyzed cross coupling reactions. This critical review reports …