Macroautophagy and microautophagy are highly conserved eukaryotic cellular processes
that degrade cytoplasmic material in lysosomes. Both pathways involve characteristic …

Mitophagy mediated by the recessive Parkinson's disease genes PINK1 and Parkin
responds to mitochondrial damage to preserve mitochondrial function. In the pathway …

Mitochondria are central hubs of cellular metabolism that also play key roles in signaling
and disease. It is therefore fundamentally important that mitochondrial quality and activity …

Cargo sequestration is a fundamental step of selective autophagy in which cells generate a
double-membrane structure termed an" autophagosome" on the surface of cargoes. NDP52 …

Autophagy is a conserved intracellular degradation pathway that generates de novo double-
membrane autophagosomes to target a wide range of material for lysosomal degradation. In …

Department of Molecular Oncology, Institute for Advanced Medical Sciences, Nippon
Medical School, Tokyo, Japan Autophagy is a self-digestive process that is conserved in …

The coexistence of cadmium (Cd) can potentiate (synergism) or reduce (antagonism) the
pesticide effects on organisms, which may change with chiral pesticide enantiomers …

Macroautophagy/autophagy is a fundamental aspect of eukaryotic biology, and the autopha
g y-related protein ATG9A is part of the core machinery facilitating this process. In addition to …

Autophagy mediates the degradation and recycling of cellular material in the lysosomal
system. Dysfunctional autophagy is associated with a plethora of diseases including …

Autophagy is an important metabolic pathway that can non-selectively recycle cellular
material or lead to targeted degradation of protein aggregates or damaged organelles …