Differential scanning calorimetry measures the heat capacity of states and the excess heat
associated with transitions that can be induced by temperature change. The integral of the …

Background The two α-crystallins (αA-and αB-crystallin) are major components of our eye
lenses. Their key function there is to preserve lens transparency which is a challenging task …

The effect of pH on the conformational behavior of Candida antartica lipase B (CaLB) has
been monitored by spectroscopic and calorimetric studies. The results obtained from far and …

With aging, human lenses lose the ability to focus on nearby objects due to decreases in
accommodative ability, a condition known as presbyopia. An increase in stiffness or …

Alpha-crystallin protein performs structural and chaperone functions in the lens and
comprises alphaA and alphaB subunits at a molar ratio of 3: 1. The highly complex alpha …

It is a challenge to formulate polymer based nanoparticles of therapeutic proteins as
excipients and process conditions affect stability and structural integrity of the protein …

Cataract is one of the major causes of blindness worldwide. Several factors including post-
translational modification, thermal and solar radiations promote cataractogenesis. The …

α-crystallin is a major structural protein in the eye lenses of vertebrates that is composed of
two relative subunits, αA and αB crystallin, which function in maintaining lens transparency …

The structural properties of α-crystallin, the major protein of the eye lens of mammals, in
aqueous solution are investigated by means of small angle X-ray and dynamic light …

While chaperone activity of alpha-crystallin (α-Crs) is important in maintaining lens
transparency that of beta-casein (β-CN) is vital to prevent the development of corpora …