Bladder cancer (BC) is the 11th most popular cancer in females and 4th in males. A lot of
efforts have been exerted to improve BC patients' care. Besides, new approaches have …

In addition to the deregulation of gene transcriptions and post-translational protein
modifications, the aberrant translation from mRNAs to proteins plays an important role in the …

Kirsten rat sarcoma virus (KRAS) mutations are frequently detected in many cancers and are
major driver genes. Therefore, KRAS inhibitors have been the subject of extensive research …

Background: microRNAs have drawn more attention due to their function on the
inflammatory process. The association between microRNA-21 (miR-21) expression and risk …

Musashi-2 (MSI2) is an evolutionally conserved RNA-binding protein and recently
considered as an attractive therapeutic target in a wide spectrum of malignancies. However …

MicroRNAs (MiRNAs), which are highly conserved and small noncoding RNAs, negatively
regulate gene expression and influence signaling pathways involved in essential biological …

Local invasion and distant metastasis are the key hallmarks in the aggressive progression of
malignant tumors, including the ability of cancer cells to detach from the extracellular matrix …

The androgen receptor (AR) pathway is critical for prostate cancer carcinogenesis and
development; however, after 18‐24 months of AR blocking therapy, patients invariably …

Bladder cancer (BLCA) acts as one of the most common malignant tumors in the urinary
system without ideal therapy. We performed the present study to explore the role and …

Objectives To assess the real‐world clinical benefit of re‐challenging chemotherapy after
pembrolizumab in patients with metastatic urothelial carcinoma (mUC), as there have been …