The β common chain cytokines GM-CSF, IL-3, and IL-5 regulate varied inflammatory
responses that promote the rapid clearance of pathogens but also contribute to pathology in …

EOSINOPHIL production can be induced in vitro by interleukin-3 (IL-3), granulocyte-
macrophage colony-stimulating factor (GM-CSF), and IL-5. Both IL-3 and GM-CSF have …

We have isolated the human cDNA homologue of a mouse helper T-cell-specific cDNA
sequence, called P600, from an activated human T-cell cDNA library. The human cDNA …

Granulocyte–macrophage colony‐stimulating factor (GM–CSF), interleukin‐3 (IL‐3), and IL‐
5 are members of a discrete family of cytokines that regulates the growth, differentiation …

Interleukin‐5 is a Th2 homodimeric cytokine involved in the differentiation, maturation,
migration, development, survival, trafficking and effector function of blood and local tissue …

Abstract INTERLEUKIN-5 (IL-5) is a lineage-specific cytokine for eosinophilpoiesis and
plays an important part in diseases associ-ated with increased eosinophils, such as …

Human interleukin 5 (hIL5) and soluble forms of its receptor α subunit were expressed in
Drosophila cells and purified to homogeneity, allowing a detailed structural and functional …

Publisher Summary The chapter summarizes advances in interleukin-5 (IL-5) and IL-soluble
receptor (IL-SR) research in the study of structure, physiologic functions, and the unique …

Interleukin-5 (IL-5) regulates the production and function of B cells, eosinophils, and
basophils. The IL-5 receptor (IL-5R) consists of two distinct membrane proteins, α and β. The …

A detailed structure-function analysis of human interleukin 5 (hIL5) has been performed. The
hIL5 receptor is composed of two different polypeptide chains, the alpha and beta subunits …