COVID-19, immunothrombosis and venous thromboembolism: biological mechanisms
J Loo, DA Spittle, M Newnham - Thorax, 2021 - thorax.bmj.com
Thrombotic events that frequently occur in COVID-19 are predominantly venous
thromboemboli (VTE) and are associated with increasing disease severity and worse clinical …
thromboemboli (VTE) and are associated with increasing disease severity and worse clinical …
Innate immunity, cytokine storm, and inflammatory cell death in COVID-19
R Karki, TD Kanneganti - Journal of Translational Medicine, 2022 - Springer
The innate immune system serves as the first line of defense against invading pathogens;
however, dysregulated innate immune responses can induce aberrant inflammation that is …
however, dysregulated innate immune responses can induce aberrant inflammation that is …
No evidence for basigin/CD147 as a direct SARS-CoV-2 spike binding receptor
The spike protein of SARS-CoV-2 is known to enable viral invasion into human cells through
direct binding to host receptors including ACE2. An alternate entry receptor for the virus was …
direct binding to host receptors including ACE2. An alternate entry receptor for the virus was …
DC/L-SIGN recognition of spike glycoprotein promotes SARS-CoV-2 trans-infection and can be inhibited by a glycomimetic antagonist
M Thépaut, J Luczkowiak, C Vivès, N Labiod… - PLoS …, 2021 - journals.plos.org
The efficient spread of SARS-CoV-2 resulted in a unique pandemic in modern history.
Despite early identification of ACE2 as the receptor for viral spike protein, much remains to …
Despite early identification of ACE2 as the receptor for viral spike protein, much remains to …
Innate immunity in protection and pathogenesis during coronavirus infections and COVID-19
RKS Malireddi, BR Sharma… - Annual Review of …, 2024 - annualreviews.org
The COVID-19 pandemic was caused by the recently emerged β-coronavirus SARS-CoV-2.
SARS-CoV-2 has had a catastrophic impact, resulting in nearly 7 million fatalities worldwide …
SARS-CoV-2 has had a catastrophic impact, resulting in nearly 7 million fatalities worldwide …
Genetic and epigenetic factors associated with increased severity of Covid‐19
Z Yildirim, OS Sahin, S Yazar… - Cell biology …, 2021 - Wiley Online Library
Since December 2019, a new form of severe acute respiratory syndrome (SARS) from a
novel strain of coronavirus (SARS coronavirus 2 [SARS‐CoV‐2]) has been spreading …
novel strain of coronavirus (SARS coronavirus 2 [SARS‐CoV‐2]) has been spreading …
Sweet drugs for bad bugs: a glycomimetic strategy against the DC-SIGN-mediated dissemination of SARS-CoV-2
The C-type lectin receptor DC-SIGN is a pattern recognition receptor expressed on
macrophages and dendritic cells. It has been identified as a promiscuous entry receptor for …
macrophages and dendritic cells. It has been identified as a promiscuous entry receptor for …
Host factors facilitating SARS‐CoV‐2 virus infection and replication in the lungs
SARS-CoV-2 is the virus causing the major pandemic facing the world today. Although,
SARS-CoV-2 primarily causes lung infection, a variety of symptoms have proven a systemic …
SARS-CoV-2 primarily causes lung infection, a variety of symptoms have proven a systemic …
An atlas connecting shared genetic architecture of human diseases and molecular phenotypes provides insight into COVID-19 susceptibility
Background While genome-wide associations studies (GWAS) have successfully elucidated
the genetic architecture of complex human traits and diseases, understanding mechanisms …
the genetic architecture of complex human traits and diseases, understanding mechanisms …
SARS-CoV-2 S glycoprotein binding to multiple host receptors enables cell entry and infection
The severe acute respiratory syndrome-related coronavirus-2 (SARS-CoV-2) infection
displays a wide array of clinical manifestations. Although some risk factors for coronavirus …
displays a wide array of clinical manifestations. Although some risk factors for coronavirus …