Insights into dyslexia genetics research from the last two decades
Dyslexia, a specific reading disability, is a common (up to 10% of children) and highly
heritable (~ 70%) neurodevelopmental disorder. Behavioral and molecular genetic …
heritable (~ 70%) neurodevelopmental disorder. Behavioral and molecular genetic …
Neurogenetics of developmental dyslexia: from genes to behavior through brain neuroimaging and cognitive and sensorial mechanisms
Developmental dyslexia (DD) is a complex neurodevelopmental deficit characterized by
impaired reading acquisition, in spite of adequate neurological and sensorial conditions …
impaired reading acquisition, in spite of adequate neurological and sensorial conditions …
Proteomic analysis of mammalian primary cilia
The primary cilium is a microtubule-based organelle that senses extracellular signals as a
cellular antenna [1]. Primary cilia are found on many types of cells in our body and play …
cellular antenna [1]. Primary cilia are found on many types of cells in our body and play …
Stages of ciliogenesis and regulation of ciliary length
P Avasthi, WF Marshall - Differentiation, 2012 - Elsevier
Cilia and flagella are highly conserved eukaryotic microtubule-based organelles that
protrude from the surface of most mammalian cells. These structures require large protein …
protrude from the surface of most mammalian cells. These structures require large protein …
Molecular genetics of dyslexia: an overview
Dyslexia is a highly heritable learning disorder with a complex underlying genetic
architecture. Over the past decade, researchers have pinpointed a number of candidate …
architecture. Over the past decade, researchers have pinpointed a number of candidate …
Distinct features of doublecortin as a marker of neuronal migration and its implications in cancer cell mobility
AA Ayanlaja, Y Xiong, Y Gao, GQ Ji, C Tang… - Frontiers in molecular …, 2017 - frontiersin.org
Neuronal migration is a critical process in the development of the nervous system. Defects in
the migration of the neurons are associated with diseases like lissencephaly, subcortical …
the migration of the neurons are associated with diseases like lissencephaly, subcortical …
Three dyslexia susceptibility genes, DYX1C1, DCDC2, and KIAA0319, affect temporo-parietal white matter structure
F Darki, M Peyrard-Janvid, H Matsson, J Kere… - Biological …, 2012 - Elsevier
BACKGROUND: Volume and integrity of white matter correlate with reading ability, but the
underlying factors contributing to this variability are unknown. METHODS: We investigated …
underlying factors contributing to this variability are unknown. METHODS: We investigated …
The genetic relationship between handedness and neurodevelopmental disorders
WM Brandler, S Paracchini - Trends in molecular medicine, 2014 - cell.com
Handedness and brain asymmetry have been linked to neurodevelopmental disorders such
as dyslexia and schizophrenia. The genetic nature of this correlation is not understood …
as dyslexia and schizophrenia. The genetic nature of this correlation is not understood …
[HTML][HTML] Identification of novel loci for pediatric cholestatic liver disease defined by KIF12, PPM1F, USP53, LSR, and WDR83OS pathogenic variants
S Maddirevula, H Alhebbi, A Alqahtani, T Algoufi… - Genetics in …, 2019 - Elsevier
Purpose Genetic testing in pediatric cholestasis can be very informative but genetic causes
have not been fully characterized. Methods Exome sequencing and positional mapping in …
have not been fully characterized. Methods Exome sequencing and positional mapping in …
Common variants in left/right asymmetry genes and pathways are associated with relative hand skill
Humans display structural and functional asymmetries in brain organization, strikingly with
respect to language and handedness. The molecular basis of these asymmetries is …
respect to language and handedness. The molecular basis of these asymmetries is …