Gaucher disease (GD) is a rare, genetic lysosomal disorder leading to lipid accumulation
and dysfunction in multiple organs. Involvement of the skeleton is one of the most prevalent …

Gaucher disease (GD) is an autosomal recessive lysosomal storage disease, caused by
deficiency of the enzyme glucocerebrosidase, required for the degradation of …

Gaucher disease is a rare and extraordinarily heterogeneous inborn error of metabolism that
exhibits diverse manifestations, a broad range of age of onset of symptoms, and a wide …

Ferritin is a ubiquitous protein that is present in most tissues as a cytosolic protein. The
major and common role of ferritin is to bind Fe2+, oxidize it and sequester it in a safe form in …

Abstract Background The Gaucher Investigative Therapy Evaluation is a national clinical
cohort of 250 patients aged 5–87 years with Gaucher disease in the United Kingdom—an …

Gaucher disease (GD) is caused by glucocerebrosidase deficiency leading to the
accumulation of sphingolipids in macrophages named “Gaucher's Cells”. These cells are …

An evaluation of the rheological properties and the effects of Momordica. charantia L.(M.
charantia) nanoparticles and polyethylene glycol (PEG) microspheres adsorbed with M …

Gaucher disease (GD) results from a deficiency of glucocerebrosidase activity and the
subsequent accumulation of the enzyme's metabolites, principally glucosylsphingosine and …

While important advances have been recently achieved in the optimization of lipid classes'
separation, information on the specific determination of medium polarity lipids such as …

RBC adhesiveness might be involved in complications such as the vaso-occlusive crisis in
SCD, thrombosis in polycythemia vera, splenic sequestration in hereditary spherocytosis …