Toolbox for distal C–H bond functionalizations in organic molecules

SK Sinha, S Guin, S Maiti, JP Biswas, S Porey… - Chemical …, 2021 - ACS Publications
Transition-metal-catalyzed C–H activation has developed a contemporary approach to the
omnipresent area of retrosynthetic disconnection. Scientific researchers have been tempted …

Metal-catalysed C–H bond activation and borylation

R Bisht, C Haldar, MMM Hassan, ME Hoque… - Chemical Society …, 2022 - pubs.rsc.org
Transition metal-catalysed direct borylation of hydrocarbons via C–H bond activation has
received a remarkable level of attention as a popular reaction in the synthesis of …

Strategic evolution in transition metal-catalyzed directed C–H bond activation and future directions

S Rej, A Das, N Chatani - Coordination Chemistry Reviews, 2021 - Elsevier
In the field of C–H bond functionalization chemistry, directed C–H bond activation strategies
are highly appreciated due to the high efficiency and selectivity of such reactions towards a …

Transition metal–catalyzed remote C─ H borylation: An emerging synthetic tool

MMM Hassan, S Guria, S Dey, J Das… - Science …, 2023 - science.org
Transition metal–catalyzed C─ H bond activation and borylation is a powerful synthetic
method that offers versatile synthetic transformation from organoboron compounds to …

Controlling Reactivity and Selectivity in the Nondirected C–H Activation of Arenes with Palladium

S Kaltenberger, M van Gemmeren - Accounts of Chemical …, 2023 - ACS Publications
Conspectus Aromatic structures are widespread motifs throughout organic chemistry, and C–
H activation has been recognized as a major tool for enabling their sustainable and efficient …

Achieving site-selectivity for C–H activation processes based on distance and geometry: a carpenter's approach

G Meng, NYS Lam, EL Lucas… - Journal of the …, 2020 - ACS Publications
The ability to differentiate between highly similar C–H bonds in a given molecule remains a
fundamental challenge in organic chemistry. In particular, the lack of sufficient steric and …

New horizons for catalysis disclosed by supramolecular chemistry

G Olivo, G Capocasa, D Del Giudice… - Chemical Society …, 2021 - pubs.rsc.org
The adoption of a supramolecular approach in catalysis promises to address a number of
unmet challenges, ranging from activity (unlocking of novel reaction pathways) to selectivity …

Recent developments in enantioselective transition metal catalysis featuring attractive noncovalent interactions between ligand and substrate

A Fanourakis, PJ Docherty, P Chuentragool… - ACS …, 2020 - ACS Publications
Enantioselective transition metal catalysis is an area very much at the forefront of
contemporary synthetic research. The development of processes that enable the efficient …

Remote steric control for undirected meta-selective C–H activation of arenes

B Ramadoss, Y Jin, S Asako, L Ilies - Science, 2022 - science.org
Regioselective functionalization of arenes remains a challenging problem in organic
synthesis. Steric interactions are often used to block sites adjacent to a given substituent, but …

Enantioselective remote C–H activation directed by a chiral cation

GR Genov, JL Douthwaite, ASK Lahdenperä… - Science, 2020 - science.org
Chiral cations have been used extensively as organocatalysts, but their application to
rendering transition metal–catalyzed processes enantioselective remains rare. This is …