Studies on psychotropic medications decrease, discontinuation, or switch have uncovered
withdrawal syndromes. The present overview aimed at analyzing the literature to illustrate …

Physiological dependence on benzodiazepines is accompanied by a withdrawal syndrome
which is typically characterized by sleep disturbance, irritability, increased tension and …

• We compared the effect of abrupt discontinuation of therapeutic doses of short half-life and
long half-life benzodiazepines in 57 benzodiazepine-dependent patients (daily use,> 1 …

The opioid epidemic is a public health problem associated with a host of negative outcomes.
Although clinicians recognize covariation between opioid misuse with anxiety and …

Globally benzodiazepines remain one of the most prescribed medication groups, especially
in the primary care setting. With such high levels of prescribing it is not surprising that …

This double-blind study involved the continuous (six to 22 weeks) treatment of 180
chronically anxious outpatients with diazepam, 15 to 40 mg/day. Our findings indicate that a …

• The possibility that panic disorder might be due to abnormal activity of endogenous ligands
of the benzodiazepine receptor was investigated with the use of the benzodiazepine …

Classical pharmacological dependence accompanied by euphoria, clinical evidence of
tolerance and escalation of dosage are very rare with the benzodiazepines. However, there …

" I am lucky to have found somewhere where sufferers can be encouraged and supported
through withdrawal. I have found many new friends, who, like me, were caught up in the web …

• We compared the effect on withdrawal severity and acute outcome of a 25% per week
taper of short half-life vs long half-life benzodiazepines in 63 benzodiazepine-dependent …