The effects of RNA methylation on immune cells development and function

LF Zha, JL Wang, X Cheng - The FASEB Journal, 2022 - Wiley Online Library
Among the more than 170 known RNA modifications, methylation modification is the most
frequent and well‐studied. Depending on where the methylation occurs, RNA methylation …

The regulatory role of N6-methyladenosine RNA modification in gastric cancer: Molecular mechanisms and potential therapeutic targets

G Li, Q Fu, C Liu, Y Peng, J Gong, S Li, Y Huang… - Frontiers in …, 2022 - frontiersin.org
N6-methyladenosinen (m6A) methylation is a frequent RNA methylation modification that is
regulated by three proteins:“writers”,“erasers”, and “readers”. The m6A modification …

METTL3 potentiates osteogenic differentiation of bone marrow mesenchymal stem cells via IGF2BP1/m6A/RUNX2

S Zhou, G Zhang, K Wang, Z Yang, Y Tan - Oral Diseases, 2024 - Wiley Online Library
Objective Maxillofacial bone defect is a critical obstacle for maxillofacial tumors and
periodontal diseases. The osteogenic differentiation of bone marrow mesenchymal stem …

Chemical Control of CRISPR Gene Editing via Conditional Diacylation Crosslinking of Guide RNAs

H Lei, T Zeng, X Ye, R Fan, W Xiong, T Tian… - Advanced …, 2023 - Wiley Online Library
Conditional control of RNA structure and function has emerged as an effective toolkit. Here,
a strategy based on a one‐step introduction of diacylation linkers and azide groups on the …

[HTML][HTML] N6-methyladenosine in vascular aging and related diseases: clinical perspectives

C Li, L Liu, S Li, YS Liu - Aging and Disease, 2024 - ncbi.nlm.nih.gov
Aging leads to progressive deterioration of the structure and function of arteries, which
eventually contributes to the development of vascular aging-related diseases. N 6 …

m6A reader IGF2BP1 accelerates apoptosis of high glucose-induced vascular endothelial cells in a m6A-HMGB1 dependent manner

A Liang, J Liu, Y Wei, Y Liao, F Wu, J Ruan, J Li - PeerJ, 2023 - peerj.com
Emerging evidence indicates that N 6-methyladenosine (m 6 A) plays a critical role in
vascular biological characteristic. In diabetes mellitus pathophysiology, high glucose (HG) …

Examining the evidence for mutual modulation between m6A modification and circular RNAs: current knowledge and future prospects

X Tang, M Guo, Y Zhang, J Lv, C Gu, Y Yang - Journal of Experimental & …, 2024 - Springer
The resistance of cancer cells to treatment significantly impedes the success of therapy,
leading to the recurrence of various types of cancers. Understanding the specific …

Identification of m6A-related biomarkers in systemic lupus erythematosus: a bioinformation-based analysis

Y Tian, K Tao, S Li, X Chen, R Wang… - Journal of …, 2024 - Taylor & Francis
Background Systemic Lupus Erythematosus (SLE), a prototypical autoimmune disorder,
presents a challenge due to the absence of reliable biomarkers for discerning organ-specific …

The Role of RNA Methylation Modification Related Genes in Prognosis and Immunotherapy of Colorectal Cancer

R Lin, R Chen, L Ye, Z Huang, X Lin… - International Journal of …, 2023 - Taylor & Francis
Background Researches showed RNA methylation genes can affect the prognosis of
tumors. Thus, the study aimed to comprehensively analyze the effects of RNA methylation …

m6A 'writer'KIAA1429 regulates the proliferation and migration of endothelial cells in atherosclerosis

J Rong, Y Jie, H Zhao - Molecular Biotechnology, 2023 - Springer
Increasing evidences have illustrated the important role of N6-methyladenosine (m6A) in
atherosclerosis (AS). However, the role of m6A modification in AS pathophysiological …