Advances in multiplexed techniques for the detection and quantification of microRNAs

T Jet, G Gines, Y Rondelez, V Taly - Chemical Society Reviews, 2021 - pubs.rsc.org
MicroRNA detection is currently a crucial analytical chemistry challenge: almost 2000
papers were referenced in PubMed in 2018 and 2019 for the keywords “miRNA detection …

RNA in extracellular vesicles

KM Kim, K Abdelmohsen, M Mustapic… - Wiley …, 2017 - Wiley Online Library
Cells release a range of membrane‐enclosed extracellular vesicles (EVs) into the
environment. Among them, exosomes and microvesicles (collectively measuring 40–1000 …

MicroRNA: biogenesis, function and role in cancer

LA MacFarlane, PR Murphy - Current genomics, 2010 - ingentaconnect.com
MicroRNAs are small, highly conserved non-coding RNA molecules involved in the
regulation of gene expression. MicroRNAs are transcribed by RNA polymerases II and III …

Glia-to-neuron transfer of miRNAs via extracellular vesicles: a new mechanism underlying inflammation-induced synaptic alterations

I Prada, M Gabrielli, E Turola, A Iorio, G D'Arrigo… - Acta …, 2018 - Springer
Recent evidence indicates synaptic dysfunction as an early mechanism affected in
neuroinflammatory diseases, such as multiple sclerosis, which are characterized by chronic …

MicroRNA expression profiles classify human cancers

J Lu, G Getz, EA Miska, E Alvarez-Saavedra, J Lamb… - nature, 2005 - nature.com
Recent work has revealed the existence of a class of small non-coding RNA species, known
as microRNAs (miRNAs), which have critical functions across various biological processes …

Oncomirs—microRNAs with a role in cancer

A Esquela-Kerscher, FJ Slack - Nature reviews cancer, 2006 - nature.com
MicroRNAs (miRNAs) are an abundant class of small non-protein-coding RNAs that function
as negative gene regulators. They regulate diverse biological processes, and bioinformatic …

[HTML][HTML] The role of microRNAs in human diseases

AM Ardekani, MM Naeini - Avicenna journal of medical …, 2010 - ncbi.nlm.nih.gov
MicroRNAs (miRNAs) are short RNA molecules which bind to target mRNAs, resulting in
translational repression and gene silencing and are found in all eukaryotic cells …

MicroRNA gene expression deregulation in human breast cancer

MV Iorio, M Ferracin, CG Liu, A Veronese, R Spizzo… - Cancer research, 2005 - AACR
MicroRNAs (miRNAs) are a class of small noncoding RNAs that control gene expression by
targeting mRNAs and triggering either translation repression or RNA degradation. Their …

[HTML][HTML] microRNAs as oncogenes and tumor suppressors

B Zhang, X Pan, GP Cobb, TA Anderson - Developmental biology, 2007 - Elsevier
microRNAs (miRNAs) are a new class of non-protein-coding, endogenous, small RNAs.
They are important regulatory molecules in animals and plants. miRNA regulates gene …

MicroRNA biogenesis: coordinated cropping and dicing

VN Kim - Nature reviews Molecular cell biology, 2005 - nature.com
The recent discovery of microRNAs (miRNAs) took many by surprise because of their
unorthodox features and widespread functions. These tiny,∼ 22-nucleotide, RNAs control …