Ferritin in the coronavirus disease 2019 (COVID‐19): a systematic review and meta‐analysis

L Cheng, H Li, L Li, C Liu, S Yan… - Journal of clinical …, 2020 - Wiley Online Library
Objective The coronavirus disease 2019 (COVID‐19) has rapidly developed into a
pandemic. Increased levels of ferritin due to cytokine storm and secondary hemophagocytic …

Silencing the cytokine storm: the use of intravenous anakinra in haemophagocytic lymphohistiocytosis or macrophage activation syndrome

P Mehta, RQ Cron, J Hartwell, JJ Manson… - The Lancet …, 2020 - thelancet.com
The term cytokine storm syndromes describes conditions characterised by a life-threatening,
fulminant hypercytokinaemia with high mortality. Cytokine storm syndromes can be genetic …

Characteristics and prognostic factors of disease severity in patients with COVID-19: The Beijing experience

Y Sun, Y Dong, L Wang, H Xie, B Li, C Chang… - Journal of …, 2020 - Elsevier
COVID-19 has become one of the worst infectious disease outbreaks of recent times, with
over 2.1 million cases and 120,000 deaths so far. Our study investigated the demographic …

Benefit of anakinra in treating pediatric secondary hemophagocytic lymphohistiocytosis

EM Eloseily, P Weiser, CB Crayne… - Arthritis & …, 2020 - Wiley Online Library
Objective To assess the benefit of the recombinant human interleukin‐1 receptor antagonist
anakinra in treating pediatric patients with secondary hemophagocytic lymphohistiocytosis …

Hemophagocytic lymphohistiocytosis

H Al-Samkari, N Berliner - Annual review of pathology …, 2018 - annualreviews.org
Hemophagocytic lymphohistiocytosis is a life-threatening disorder characterized by
unbridled activation of cytotoxic T lymphocytes, natural killer (NK) cells, and macrophages …

Adult haemophagocytic syndrome

M Ramos-Casals, P Brito-Zerón, A López-Guillermo… - The Lancet, 2014 - thelancet.com
Haemophagocytic syndromes (haemophagocytic lymphohistiocytosis) have a wide range of
causes, symptoms, and outcomes, but all lead to a hyperinflammatory response and organ …

Hemophagocytic lymphohistiocytosis

TS Ponnatt, CM Lilley, KM Mirza - Archives of Pathology & …, 2022 - meridian.allenpress.com
Context.—Hemophagocytic lymphohistiocytosis (HLH) is a rare, life-threatening disorder of
immune regulation that can eventually result in end-organ damage and death. HLH is …

Macrophage activation syndrome in adults: recent advances in pathophysiology, diagnosis and treatment

SJ Carter, RS Tattersall, AV Ramanan - Rheumatology, 2019 - academic.oup.com
Haemophagocytic lymphohistiocytosis (HLH) is a hyperinflammatory syndrome, which if not
promptly treated, can lead rapidly to critical illness and death. HLH is termed macrophage …

Hemophagocytic lymphohistiocytosis: review of etiologies and management

MR George - Journal of blood medicine, 2014 - Taylor & Francis
Hemophagocytic lymphohistiocytosis (HLH) covers a wide array of related life-threatening
conditions featuring ineffective immunity characterized by an uncontrolled …

How I treat hemophagocytic lymphohistiocytosis

MB Jordan, CE Allen, S Weitzman… - Blood, The Journal …, 2011 - ashpublications.org
Hemophagocytic lymphohistiocytosis (HLH) is a syndrome of pathologic immune activation,
occurring as either a familial disorder or a sporadic condition, in association with a variety of …