Insulin-like growth factor 2 mRNA-binding protein 1 (IGF2BP1) in cancer

X Huang, H Zhang, X Guo, Z Zhu, H Cai… - Journal of hematology & …, 2018 - Springer
The insulin-like growth factor-2 mRNA-binding protein 1 (IGF2BP1) plays essential roles in
embryogenesis and carcinogenesis. IGF2BP1 serves as a post-transcriptional fine-tuner …

LncRNAs as potential diagnostic and prognostic biomarkers in gastric cancer: a novel approach to personalized medicine

S Fattahi, M Kosari‐Monfared… - Journal of cellular …, 2020 - Wiley Online Library
Gastric cancer is the third leading cause of cancer death with 5‐year survival rate of about
30–35%. Since early detection is associated with decreased mortality, identification of novel …

LncRNA structural characteristics in epigenetic regulation

C Wang, L Wang, Y Ding, X Lu, G Zhang… - International Journal of …, 2017 - mdpi.com
The rapid development of new generation sequencing technology has deepened the
understanding of genomes and functional products. RNA-sequencing studies in mammals …

Knockdown of long non-coding RNA HOTAIR inhibits cisplatin resistance of gastric cancer cells through inhibiting the PI3K/Akt and Wnt/β-catenin signaling pathways …

C Cheng, Y Qin, Q Zhi, J Wang, C Qin - International journal of biological …, 2018 - Elsevier
Abstract HOX transcript antisense RNA (HOTAIR), a well-known long non-coding RNA
(lncRNA), has been reported to be related to cisplatin (DDP) resistance in gastric cancers …

GAERF: predicting lncRNA-disease associations by graph auto-encoder and random forest

QW Wu, JF Xia, JC Ni, CH Zheng - Briefings in bioinformatics, 2021 - academic.oup.com
Predicting disease-related long non-coding RNAs (lncRNAs) is beneficial to finding of new
biomarkers for prevention, diagnosis and treatment of complex human diseases. In this …

Long non-coding RNA UCA1 regulates the expression of Snail2 by miR-203 to promote hepatocellular carcinoma progression

JN Xiao, TH Yan, RM Yu, Y Gao, WL Zeng… - Journal of cancer …, 2017 - Springer
Purpose Long non-coding RNA (LncRNA) urothelial carcinoma-associated 1 (UCA1) is
reported to be dysregulated in hepatocellular carcinoma (HCC) progression. However, the …

Modulation of IGF2BP1 by long non-coding RNA HCG11 suppresses apoptosis of hepatocellular carcinoma cells via MAPK signaling transduction

Y Xu, Y Zheng, H Liu, T Li - … journal of oncology, 2017 - spandidos-publications.com
Hepatocellular carcinoma (HCC) is a common malignancy of the liver. HCG11 is a member
of long non‑coding family, upregulation of which in HCC was proved by our previous study …

Long non-coding RNAs: the new horizon of gene regulation in ovarian cancer

T Worku, D Bhattarai, D Ayers, K Wang… - Cellular Physiology and …, 2017 - karger.com
Long non-coding RNAs (lncRNAs), a class of non-coding transcripts, have recently been
emerging with heterogeneous molecular actions, adding a new layer of complexity to gene …

A review of research progress in multidrug-resistance mechanisms in gastric cancer

T Ruan, W Liu, K Tao, C Wu - OncoTargets and therapy, 2020 - Taylor & Francis
Gastric cancer is one of the most common malignant tumors, and it is also one of the leading
causes of cancer death worldwide. Because of its insidious symptoms and lack of early …

[HTML][HTML] Long non-coding RNA LUCAT1 promotes proliferation and invasion in gastric cancer by regulating miR-134-5p/YWHAZ axis

J Chi, T Liu, C Shi, H Luo, Z Wu, B Xiong, S Liu… - Biomedicine & …, 2019 - Elsevier
Purpose The aim of this study was to research the function of lncRNA LUCAT1 in gastric
cancer. Methods Human gastric cancer tissues and paracancer tissues were obtained from …