IgGs are essential soluble components of the adaptive immune response that evolved to protect the body from infection. Compared with other immunoglobulins, the role of IgGs is …
M Pyzik, KMK Sand, JJ Hubbard, JT Andersen… - Frontiers in …, 2019 - frontiersin.org
Antibodies are essential components of an adaptive immune response. Immunoglobulin G (IgG) is the most common type of antibody found in circulation and extracellular fluids …
JT Ryman, B Meibohm - CPT: pharmacometrics & systems …, 2017 - Wiley Online Library
Monoclonal antibodies (mAbs) have developed in the last two decades into the backbone of pharmacotherapeutic interventions in a variety of indications, with currently more than 40 …
Of the five immunoglobulin isotypes, immunoglobulin G (IgG) is most abundant in human serum. The four subclasses, IgG1, IgG2, IgG3, and IgG4, which are highly conserved, differ …
In this contribution, we review the molecular and physiological barriers to oral delivery of peptides and nanoparticles. We discuss the opportunities and predictivity of various in vitro …
Immunoglobulins form an important component of the immunological activity found in milk and colostrum. They are central to the immunological link that occurs when the mother …
The neonatal Fc receptor for IgG (FcRn) has been well characterized in the transfer of passive humoral immunity from a mother to her fetus. In addition, throughout life, FcRn …
Targeting of drugs and their carrier systems by using receptor-mediated endocytotic pathways was in its nascent stages 25years ago. In the intervening years, an explosion of …
KMK Sand, M Bern, J Nilsen, HT Noordzij… - Frontiers in …, 2015 - frontiersin.org
The neonatal Fc receptor (FcRn) was first found to be responsible for transporting antibodies of the immunoglobulin G (IgG) class from the mother to the fetus or neonate as well as for …