Movement, the fundamental component of behavior and the principal extrinsic action of the
brain, is produced when skeletal muscles contract and relax in response to patterns of action …

Persistent neural activity refers to a sustained change in action potential discharge that long
outlasts a stimulus. It is found in a diverse set of brain regions and organisms and several in …

After chronic spinal cord injury motoneurons exhibit large plateau potentials (sustained
depolarizations triggered by brief inputs) that play a primary role in the development of …

Communication between neurons can occur chemically via synaptic transmission. This
communication process begins when an invading depolarization opens voltage-gated …

Dendrites contain voltage-sensitive conductances that, in vivo, can be influenced by
neuromodulatory inputs. In spinal motoneurons, dendrites have voltage-activated persistent …

To investigate the mechanisms of persistent neural activity, we obtained in vivo intracellular
recordings from neurons in an oculomotor neural integrator of the goldfish during …

The calculation and memory of position variables by temporal integration of velocity signals
is essential for posture, the vestibulo-ocular reflex (VOR) and navigation. Integrator neurons …

The effects of serotonin (5-HT) on intrinsic properties of spinal motoneurons were
investigated with intracellular recordings in a slice preparation from adult turtles. In 55% of …

Voltage-sensitive ionic currents shape both the firing properties of neurons and their
synaptic integration within neural networks that drive rhythmic motor patterns. Persistent …

Since their discovery in the late 19th century our conception of motoneurons has steadily
evolved. Motoneurons share the same general function: they drive the contraction of muscle …