Activity-based diagnostics: recent advances in the development of probes for use with diverse detection modalities
Abnormal enzyme expression and activity is a hallmark of many diseases. Activity-based
diagnostics are a class of chemical probes that aim to leverage this dysregulated metabolic …
diagnostics are a class of chemical probes that aim to leverage this dysregulated metabolic …
Novel technologies for the diagnosis of urinary tract infections
T Bermudez, JE Schmitz, M Boswell… - Journal of Clinical …, 2025 - journals.asm.org
Urinary tract infections (UTIs) impose a substantial burden on patient quality of life and urine
testing accounts for the majority of workload in many clinical microbiology laboratories …
testing accounts for the majority of workload in many clinical microbiology laboratories …
Trends in prevalence of extended-spectrum beta-lactamase-producing Escherichia coli isolated from patients with community- and healthcare-associated bacteriuria …
E Raphael, MM Glymour, HF Chambers - Antimicrobial Resistance & …, 2021 - Springer
Background The prevalence of infections caused by extended-spectrum beta-lactamase
producing Escherichia coli (ESBL-E. coli) is increasing worldwide, but the setting in which …
producing Escherichia coli (ESBL-E. coli) is increasing worldwide, but the setting in which …
Superhydrophobic rotation-chip for computer-vision identification of drug-resistant bacteria
The transport, distribution, and mixing of microfluidics often require additional instruments,
such as pumps and valves, which are not feasible when operated in point-of-care (POC) …
such as pumps and valves, which are not feasible when operated in point-of-care (POC) …
Application of a solid-phase microextraction-gas chromatography-mass spectrometry/metal oxide sensor system for detection of antibiotic susceptibility in urinary tract …
Purpose Antibiotic resistance is widespread throughout the world and represents a serious
health concern. There is an urgent need for the development of novel tools for rapidly …
health concern. There is an urgent need for the development of novel tools for rapidly …
A rapid, antibiotic susceptibility test for multidrug-resistant, Gram-negative bacterial uropathogens using the biochemical assay, DETECT
N Jackson, CA Borges, NJ Tarlton, A Resendez… - Journal of …, 2021 - Elsevier
The increasing prevalence of extended spectrum β-lactamases (ESBLs) and plasmid-
mediated AmpC (pAmpC) β-lactamases among Enterobacterales threatens our ability to …
mediated AmpC (pAmpC) β-lactamases among Enterobacterales threatens our ability to …
A self-immolative linker that releases thiols detects penicillin amidase and nitroreductase with high sensitivity via absorption spectroscopy
This article reports the synthesis and characterization of a novel self-immolative linker,
based on thiocarbonates, which releases a free thiol upon activation via enzymes. We …
based on thiocarbonates, which releases a free thiol upon activation via enzymes. We …
Comparación de desenlaces clínicos entre infección urinaria por gérmenes Blee y no Blee en un hospital base de Trujillo
FL Vega Moreno - 2023 - alicia.concytec.gob.pe
Determinar la diferencia en los desenlaces clínicos entre infección urinaria por gérmenes
BLEE y no BLEE en un hospital base de Trujillo. Material y métodos: Se llevó a cabo un …
BLEE y no BLEE en un hospital base de Trujillo. Material y métodos: Se llevó a cabo un …