ImmunoPET: concept, design, and applications

W Wei, ZT Rosenkrans, J Liu, G Huang, QY Luo… - Chemical …, 2020 - ACS Publications
Immuno-positron emission tomography (immunoPET) is a paradigm-shifting molecular
imaging modality combining the superior targeting specificity of monoclonal antibody (mAb) …

Radioactive transition metals for imaging and therapy

E Boros, AB Packard - Chemical reviews, 2018 - ACS Publications
Nuclear medicine is composed of two complementary areas, imaging and therapy. Positron
emission tomography (PET) and single-photon imaging, including single-photon emission …

Current Perspectives on 89Zr-PET Imaging

JK Yoon, BN Park, EK Ryu, YS An, SJ Lee - International Journal of …, 2020 - mdpi.com
89Zr is an emerging radionuclide that plays an essential role in immuno-positron emission
tomography (PET) imaging. The long half-life of 89Zr (t1/2= 3.3 days) is favorable for …

Zirconium immune-complexes for PET molecular imaging: current status and prospects

L Melendez-Alafort, G Ferro-Flores, L De Nardo… - Coordination Chemistry …, 2023 - Elsevier
Diagnostic molecular images, obtained by positron emission tomography (PET), have
successfully functioned as sensitive tools for detecting and monitoring the treatment of …

[HTML][HTML] Target manufacturing by spark plasma sintering for efficient 89Zr production

S Cisternino, E Cazzola, H Skliarova, J Amico… - Nuclear Medicine and …, 2022 - Elsevier
Abstract Zirconium-89 (89 Zr) is an emerging radionuclide for positron emission tomography
(PET), with nuclear properties suitable for imaging slow biological processes in cellular …

Targeted PET/MRI imaging super probes: a critical review of opportunities and challenges

A Kastelik-Hryniewiecka, P Jewula… - International Journal …, 2022 - Taylor & Francis
Recently, the demand for hybrid PET/MRI imaging techniques has increased significantly,
which has sparked the investigation into new ways to simultaneously track multiple …

Production of zirconium-88 via proton irradiation of metallic yttrium and preparation of target for neutron transmission measurements at DICER

AV Matyskin, A Stamatopoulos, EM O'Brien… - Scientific Reports, 2023 - nature.com
A process for the production of tens to hundreds of GBq amounts of zirconium-88 (88Zr)
using proton beams on yttrium was developed. For this purpose, yttrium metal targets (≈ 20 …

Radiolysis reduction in liquid solution targets for the production of 89Zr

NA Zacchia, DM Martinez, C Hoehr - Applied Radiation and Isotopes, 2020 - Elsevier
Increased interest in radiometals for nuclear medicine and imaging can be hampered by
radionuclide supply. 89 Zr for example, is a PET imaging nuclide for which no radionuclide …

Two bifunctional desferrioxamine chelators for bioorthogonal labeling of biovectors with zirconium-89

F Gao, C Ieritano, KT Chen, GM Dias… - Organic & …, 2018 - pubs.rsc.org
We report two bifunctional chelators, DFO-Cys and DFO-CBT, to label biovectors with
zirconium-89 according to the 2-cyanobenzothiazole/1, 2-aminothiol cycloaddition. Their …

Identification and quantification of radioactive impurities in medical radionuclides

A Al-Obaidi - 2019 - orca.cardiff.ac.uk
The presence of radioactive impurities in radionuclides that are used for medical
applications may adversely affect the quality of diagnostic images and increase radiation …