Mechanisms of stereodirecting participation and ester migration from near and far in glycosylation and related reactions

AA Hettikankanamalage, R Lassfolk, FS Ekholm… - Chemical …, 2020 - ACS Publications
This review is the counterpart of a 2018 Chemical Reviews article (Adero, PO; Amarasekara,
H.; Wen, P.; Bohé, L.; Crich, D. Chem. Rev. 2018, 118, 8242–8284) that examined the …

Advances in protecting groups for oligosaccharide synthesis

B Ghosh, SS Kulkarni - Chemistry–An Asian Journal, 2020 - Wiley Online Library
Carbohydrates contain numerous hydroxyl groups and sometimes amine functionalities
which lead to a variety of complex structures. In order to discriminate each hydroxyl group for …

Synthesis of Alpha-Linked Glucosides from Soybean Isoflavone Aglycones Using Amylosucrase from Deinococcus geothermalis

YS Jung, HG Kim, SM Oh, DY Lee… - Journal of Agricultural …, 2023 - ACS Publications
Soybean isoflavone aglycones (SIAs) have many biological activities but are poorly water-
soluble in the human body. Glycosylation provides structural diversity to SIAs and can alter …

Ullmann-type N-arylation of anilines with alkyl (aryl) sulfonium salts

ZY Tian, CP Zhang - Chemical Communications, 2019 - pubs.rsc.org
A palladium/copper-cocatalyzed Ullmann-type N-arylation of anilines using alkyl (aryl)
sulfonium triflates as arylation reagents has been accomplished. The reaction enabled Caryl …

Beyond GalNAc! Drug delivery systems comprising complex oligosaccharides for targeted use of nucleic acid therapeutics

J O'Sullivan, J Muñoz-Muñoz, G Turnbull, N Sim… - RSC …, 2022 - pubs.rsc.org
Nucleic Acid Therapeutics (NATs) are establishing a leading role for the management and
treatment of genetic diseases following FDA approval of nusinersen, patisiran, and givosiran …

Chiral auxiliaries: Usefullness in stereoselective glycosylation reactions and their synthetic applications

A Khanam, A Tiwari, PK Mandal - Carbohydrate Research, 2020 - Elsevier
Oligosaccharides play a very important role in biological system and structure-activity
relationships that is why it has a lot of application to medicinal chemistry and development of …

Efficient Synthesis of 2-OH Thioglycosides from Glycals Based on the Reduction of Aryl Disulfides by NaBH4

YF Guo, T Luo, GJ Feng, CY Liu, H Dong - Molecules, 2022 - mdpi.com
An improved method to efficiently synthesize 2-OH thioaryl glycosides starting from
corresponding per-protected glycals was developed, where 1, 2-anhydro sugars were …

Bent Bond/Antiperiplanar Hypothesis: Modulating the Reactivity and the Selectivity in the Glycosylation of Bicyclic Pyranoside Models

JF Parent, G Deslongchamps… - The Journal of Organic …, 2020 - ACS Publications
Glycosylation reactions were performed on a series of bicyclic C2-substituted pyranoside
models to isolate and analyze factors that control the glycosylation stereoselectivities …

1, 2-cis O-glycosylation methods

D Takahashi, K Toshima - … Glycoscience: Second Edition, 2021 - keio.elsevierpure.com
1,2-cis O-Glycosylation Methods — Keio University メインナビゲーションにスキップ 検索に
スキップ メインコンテンツにスキップ Keio University ホーム Keio University Logo ヘルプ&FAQ …

C2‐Cyanomethyl (CNMe) Ether‐Protected Glycosyl Trichloroacetimidate Donors for Stereoselective β‐O‐Glycosylations

M Rahaman Molla, R Thakur, A Aghi… - European Journal of …, 2023 - Wiley Online Library
Stereoselective construction of glycosidic linkages have emerged as one of the pivotal
aspects for the synthesis of complex oligosaccharide assemblies. We herein report C2 …