Chemotherapy-induced peripheral neuropathy (CIPN) is one of the most frequent side
effects caused by antineoplastic agents, with a prevalence from 19% to over 85%. Clinically …

This review provides an update on the current clinical and preclinical understanding of
chemotherapy induced peripheral neuropathy (CIPN). The overview of the clinical syndrome …

Chronic pain is associated with abnormal excitability of the somatosensory system and
remains poorly treated in the clinic. Potassium (K+) channels are crucial determinants of …

Chemotherapy-induced peripheral neuropathy (CIPN) is a debilitating and painful condition
seen in patients undergoing treatment with common agents such as vincristine, paclitaxel …

Brain cancer and leukemia are the most common cancers diagnosed in the pediatric
population and are often treated with lifesaving chemotherapy. However, chemotherapy …

The burdensome condition of chemotherapy-induced peripheral neuropathy occurs with
various chemotherapeutics, including bortezomib, oxaliplatin, paclitaxel and vincristine. The …

One of the most relevant dose-limiting adverse effects of platinum drugs is the development
of a sensory peripheral neuropathy that highly impairs the patients' quality of life. Nowadays …

Chemotherapy-induced peripheral neuropathy (CIPN) is a common, debilitating, and dose-
limiting side effect of many chemotherapy regimens yet has limited treatments due to …

Oxaliplatin is a platinum-organic drug with antineoplastic properties used for colorectal
cancer. With respect to the other platinum derivates oxaliplatin induces only a mild …

Background The potential mechanisms of microRNA-1 (miR-1) in the electrical remodeling
of atrial fibrillation remain unclear. The purpose of this study was to evaluate the effects of …