Classical Hodgkin lymphoma (cHL) and anaplastic lymphoma kinase-positive, anaplastic
large cell lymphoma (ALK+ ALCL) are B and T cell lymphomas respectively, which express …

For years, the biochemical processes that are triggered by harmful and non-harmful stimuli
at the central nervous system level have been extensively studied by the scientific …

Background Recurrence of retinoblastoma (RB) following chemoreduction is common and is
often managed with local (intra-arterial/intravitreal) chemotherapy. However, some tumors …

The transcriptional machinery is composed of numerous factors that help to regulate gene
expression in cells. The function and the fundamental role of transcription factors in different …

Existing approaches to therapeutic gene transfer are marred by the transient nature of gene
expression following non-integrative gene delivery and by safety concerns due to the …

For years, the biochemical processes that are triggered by harmful and non-harmful stimuli
at the central nervous system level have been extensively studied by the scientific …

Osteosarcoma is the most common type of pediatric bone tumor. Despite great advances in
chemotherapy during the past decades, the survival rates of osteosarcoma patients remain …

Development of theranostic nanosystems integrating cascaded surface-enhanced Raman
scattering (SERS) imaging and gene silencing therapy for accurate cancer diagnosis and …

Background C-Jun, a critical component of AP-1, exerts essential functions in various
tumors, including melanoma, and is believed to be a druggable target for cancer therapy …

Simple Summary As convergence points of signaling cascades, transcription factors (TFs)
play a crucial role in cell physiology, including B cell differentiation, and are deregulated in …