Clusterin (CLU) or APOJ is a multifunctional glycoprotein that has been implicated in several
physiological and pathological states, including Alzheimer's disease (AD). With a prominent …

In the last years, clusterin, a challenging and paradoxical apolipoprotein, has been of
growing interest amongst a rising number of scientists. This enigmatic protein is present in …

Genetic variation in clusterin gene, also known as apolipoprotein J, has been associated
with Alzheimer's disease (AD) through replicated genome-wide studies, and plasma …

Clusterin (CLU) was the first reported secreted mammalian chaperone and impacts on
serious diseases associated with inappropriate extracellular protein aggregation. Many …

The biological functions of clusterin (CLU, also known as ApoJ, SGP2, TRPM-2, CLI) have
been puzzling the researchers since its first discovery in the early 80's. We know that CLU is …

For years, clusterin has been recognized as a secreted protein and a large number of works
demonstrated that this ubiquitously expressed protein has multiple activities. Among the …

Clusterin (CLU) is an evolutionary conserved molecular chaperone present in different
human tissues and fluids and established to be a significant cancer regulator. It controls …

Aims Secretory clusterin (sCLU) plays an important role in tumor development and cancer
progression. However, the molecular mechanisms and physiological functions of sCLU in …

Alzheimer's disease (AD) is considered a chronic and debilitating neurological illness that is
increasingly impacting older-age populations. Some proteins, including clusterin (CLU or …

Transforming growth factor (TGF)-β plays a dual role in tumorigenesis, switching from acting
as a growth inhibitory tumor suppressor early in the process, to a tumor promoter in late …