The East Asian paradox: an updated position statement on the challenges to the current antithrombotic strategy in patients with cardiovascular disease

HK Kim, US Tantry, SC Smith Jr… - Thrombosis and …, 2021 - thieme-connect.com
East Asian patients have reduced anti-ischemic benefits and increased bleeding risk during
antithrombotic therapies compared with Caucasian patients. As potent P2Y 12 receptor …

Consensus and update on the definition of on-treatment platelet reactivity to adenosine diphosphate associated with ischemia and bleeding

US Tantry, L Bonello, D Aradi, MJ Price… - Journal of the American …, 2013 - jacc.org
Dual antiplatelet therapy with aspirin and a P2Y12 receptor blocker is a key strategy to
reduce platelet reactivity and to prevent thrombotic events in patients treated with …

Expert consensus document: World Heart Federation expert consensus statement on antiplatelet therapy in East Asian patients with ACS or undergoing PCI

GN Levine, Y Jeong, S Goto… - Nature reviews …, 2014 - search.proquest.com
Guideline recommendations on the use of dual antiplatelet therapy (DAPT) in patients with
acute coronary syndromes and in those undergoing percutaneous coronary intervention …

“East asian paradox”: challenge for the current antiplatelet strategy of “one-guideline-fits-all races” in acute coronary syndrome

YH Jeong - Current cardiology reports, 2014 - Springer
Clinical experiences have suggested that East Asians show the higher risk of warfarin-
related intracranial hemorrhage compared with Westerners. Therefore, different target of the …

[HTML][HTML] Acute coronary syndrome in the Asia-Pacific region

MY Chan, X Du, D Eccleston, C Ma… - international Journal of …, 2016 - Elsevier
More than 4.2 billion inhabitants populate the Asia-Pacific region. Acute coronary syndrome
(ACS) is now a major cause of death and disability in this region with in-hospital mortality …

Platelet function tests in clinical cardiology: unfulfilled expectations

DA Gorog, V Fuster - Journal of the American College of Cardiology, 2013 - jacc.org
This review is a critical evaluation of publications in the past decade on the usefulness of
platelet function tests (PFTs) in clinical cardiology, in aiding diagnosis, predicting risk, and …

Comparison of short-term clinical outcomes between ticagrelor versus clopidogrel in patients with acute myocardial infarction undergoing successful revascularization; …

KH Park, MH Jeong, Y Ahn, TH Ahn, KB Seung… - International journal of …, 2016 - Elsevier
Background Although ticagrelor has been well-known to improve clinical outcomes in
patients with acute myocardial infarction (AMI) without increased bleeding risk, its clinical …

2018 update of expert consensus statement on antiplatelet therapy in East Asian patients with ACS or undergoing PCI

Y Huo, YH Jeong, Y Gong, D Wang, B He, J Chen… - Science Bulletin, 2019 - Elsevier
East Asians are the most populous race in the world and their health status is an important
global issue. Compared with Caucasian populations, East Asian patients have a different …

World Heart Federation expert consensus statement on antiplatelet therapy in East Asian patients with ACS or undergoing PCI

GN Levine, YH Jeong, S Goto, JL Anderson, Y Huo… - Global heart, 2014 - Elsevier
Guideline recommendations on the use of dual antiplatelet therapy (DAPT) in patients with
acute coronary syndromes and in those undergoing percutaneous coronary intervention …

High Platelet Reactivity Combined with CYP2C19 Genotype in Predicting Outcomes in East Asian Patients Undergoing Percutaneous Coronary Intervention

SE Kim, HS Jeon, TH Go, JH Lee… - Clinical …, 2023 - Wiley Online Library
Loss‐of‐function (LoF) alleles of cytochrome P450 2C19 (CYP2C19), which are prevalent in
East Asians, are linked to high platelet reactivity (HPR) phenotype and poor prognosis. We …