Resveratrol: a review of preclinical studies for human cancer prevention

M Athar, JH Back, X Tang, KH Kim, L Kopelovich… - Toxicology and applied …, 2007 - Elsevier
The search for novel and effective cancer chemopreventive agents has led to the
identification of various naturally occurring compounds one of which is resveratrol (trans-3 …

Resveratrol as a chemopreventive agent: a promising molecule for fighting cancer

D Delmas, A Lançon, D Colin, B Jannin… - Current drug …, 2006 - ingentaconnect.com
Resveratrol (3, 4', 5 tri-hydroxystilbene) is a phytoalexin produced in hudge amount in
grapevine skin in response to infection by Bothrytis cinerea. This production of resveratrol …

Phytoestrogens and breast cancer prevention: possible mechanisms of action

SM Mense, TK Hei, RK Ganju… - Environmental health …, 2008 - ehp.niehs.nih.gov
Objective Phytoestrogens display an array of pharmacologic properties, and in recent years
investigation of their potential as anticancer agents has increased dramatically. In this article …

Airborne urban particles (Milan winter-PM2. 5) cause mitotic arrest and cell death: Effects on DNA, mitochondria, AhR binding and spindle organization

M Gualtieri, J Øvrevik, S Mollerup, N Asare… - Mutation Research …, 2011 - Elsevier
Airborne particulate matter (PM) is considered to be an important contributor to lung
diseases. In the present study we report that Milan winter-PM2. 5 inhibited proliferation in …

Resveratrol, a phytochemical inducer of multiple cell death pathways: apoptosis, autophagy and mitotic catastrophe

D Delmas, E Solary, N Latruffe - Current medicinal chemistry, 2011 - ingentaconnect.com
Cancers are the largest cause of mortality and morbidity in industrialized countries. In the
field of the medicinal chemistry of natural products, numerous studies have reported …

Fighting cancer with red wine? Molecular mechanisms of resveratrol

TE Kraft, D Parisotto, C Schempp… - Critical reviews in food …, 2009 - Taylor & Francis
Resveratrol, a red wine constituent, has been known for its cardioprotective effects. Recent
data give ample evidence that resveratrol can act as a chemopreventive agent as well …

Predicting the physiological relevance of in vitro cancer preventive activities of phytochemicals1

LM Howells, EP Moiseeva, CP Neal… - Acta …, 2007 - Wiley Online Library
There is growing interest in the ability of phytochemicals to prevent chronic diseases, such
as cancer and heart disease. However, some of these agents have poor bioavailability and …

Resveratrol as an inhibitor of carcinogenesis

JM Pezzuto - Pharmaceutical Biology, 2008 - Taylor & Francis
Given the high probability of developing cancer over the period of a normal life span, cancer
chemoprevention provides an attractive therapeutic strategy for the delay or reversal of this …

Anthocyanin-rich grape extract blocks breast cell DNA damage

KW Singletary, KJ Jung, M Giusti - Journal of medicinal food, 2007 - liebertpub.com
Anthocyanins, belonging to the flavonoid family of phytochemicals, have received attention
as agents that may have potential in preventing chronic diseases such as cardiovascular …

Purple grape juice inhibits 7, 12-dimethylbenz [a] anthracene (DMBA)-induced rat mammary tumorigenesis and in vivo DMBA-DNA adduct formation

KJ Jung, MA Wallig, KW Singletary - Cancer letters, 2006 - Elsevier
There has been considerable interest in identifying specific foods and phytochemicals that
may have breast cancer preventive properties. Concord grapes are rich in polyphenolic …