Targeting cancer cells with nanotherapeutics and nanodiagnostics: Current status and future perspectives
Nanotechnology is reshaping health care strategies and is expected to exert a tremendous
impact in the coming years offering better healthcare facilities. It has led to not only …
impact in the coming years offering better healthcare facilities. It has led to not only …
Smart chemistry-based nanosized drug delivery systems for systemic applications: a comprehensive review
This review focuses on the smart chemistry that has been utilized in developing polymer-
based drug delivery systems over the past 10 years. We provide a comprehensive overview …
based drug delivery systems over the past 10 years. We provide a comprehensive overview …
Development of a graphene oxide nanocarrier for dual-drug chemo-phototherapy to overcome drug resistance in cancer
Despite tremendous progress in chemotherapy, drug resistance remains a major challenge
for anticancer treatment. The combinations of chemo-photothermal and chemo-chemo …
for anticancer treatment. The combinations of chemo-photothermal and chemo-chemo …
Oral delivery of pH-responsive alginate microbeads incorporating folic acid-grafted solid lipid nanoparticles exhibits enhanced targeting effect against colorectal …
K Rajpoot, SK Jain - International journal of biological macromolecules, 2020 - Elsevier
To achieve an enhanced anticancer effect of drug to treat colorectal cancer, a dual-targeted
(ie, ligand-tailored and pH-triggered) multiparticulate system has been designed to deliver …
(ie, ligand-tailored and pH-triggered) multiparticulate system has been designed to deliver …
PEGylated lipid bilayer-supported mesoporous silica nanoparticle composite for synergistic co-delivery of axitinib and celastrol in multi-targeted cancer therapy
Small-molecule drug combination therapies are an attractive approach to enhancing cancer
chemotherapeutic responses. Therefore, this study aimed to investigate the potential of …
chemotherapeutic responses. Therefore, this study aimed to investigate the potential of …
Engineering of cell microenvironment-responsive polypeptide nanovehicle co-encapsulating a synergistic combination of small molecules for effective chemotherapy …
In this study, we report a facile method to construct a bioactive (poly (phenylalanine)-b-poly
(l-histidine)-b-poly (ethylene glycol) polypeptide nanoconstruct to co-load doxorubicin (DOX) …
(l-histidine)-b-poly (ethylene glycol) polypeptide nanoconstruct to co-load doxorubicin (DOX) …
Multimodal selenium nanoshell-capped Au@mSiO2 nanoplatform for NIR-responsive chemo-photothermal therapy against metastatic breast cancer
Multimodal therapeutic agents based on novel nanomaterials for multidrug resistance have
attracted increasing attention in cancer therapy. In this study, we describe the construction of …
attracted increasing attention in cancer therapy. In this study, we describe the construction of …
Irinotecan-encapsulated double-reverse thermosensitive nanocarrier system for rectal administration
Intravenously administered for the treatment of rectum cancer, irinotecan produces severe
side effects due to very high plasma concentrations. A novel irinotecan-encapsulated double …
side effects due to very high plasma concentrations. A novel irinotecan-encapsulated double …
Paclitaxel and etoposide co-loaded polymeric nanoparticles for the effective combination therapy against human osteosarcoma
B Wang, XC Yu, SF Xu, M Xu - Journal of nanobiotechnology, 2015 - Springer
Background The combination of chemotherapeutic drugs with different pharmacological
action has emerged as a promising therapeutic strategy in the treatment of cancers. Present …
action has emerged as a promising therapeutic strategy in the treatment of cancers. Present …
Advanced nanoscale drug delivery systems for bone cancer therapy
Bone tumors are relatively rare, which are complex cancers and primarily involve the long
bones and pelvis. Bone cancer is mainly categorized into osteosarcoma (OS) …
bones and pelvis. Bone cancer is mainly categorized into osteosarcoma (OS) …