Cisplatin (CDDP) has been widely used as a chemotherapeutic agent for solid tumors. The
most common side effect of CDDP is nephrotoxicity, and many efforts have been made in the …

Nephrotoxicity is the major limitation for the clinical use of cisplatin as an anti-tumoural drug.
Intracellular effects of cisplatin cause tubular damage and tubular dysfunction with sodium …

Despite the enormous advances made in the field of oncology, no solution to the side effect
of nephrotoxicity caused by cisplatin used as an antineoplastic agent for approximately 40 …

Background: This study was performed to effects of garlic and lemon juice mixture on lipid
profile and some cardiovascular risk factors in people 30–60 years old with moderate …

Sex and age influence susceptibility to acute kidney injury (AKI), with young females
exhibiting lowest incidence. In these studies, we investigated mechanisms which may …

Materials and Methods Low dose of CP (1 mg/kg/day; ip) was administered daily to male
and female Wistar rats for 15 consecutive days. Serum creatinine (Cr), blood urea nitrogen …

Apoptotic signaling pathways are involved in acute kidney injury (AKI) induced by the
antineoplastic drug cisplatin (Cis). Mechanical stress is known to increase interleukin (IL) …

Purpose: Symptoms and disorders related to menopause and its associated estrogen
deficiency have become a considerable health concern worldwide. Ovarian hormone …

Background: Renal ischemia-reperfusion (RIR) is the main cause of renal failure. The
incidence of RIR injury seems to be gender-related due to female sex hormone; estrogen …

Menopause is an important physiological event associated with structural and functional
changes in the kidneys. An animal model of bilateral ovariectomy was used to study the …