Fungal infections cause severe and life-threatening complications especially in
immunocompromised individuals. Antifungals targeting cellular machinery and cell …

Controlled release formulation of pesticides based on microcapsules is a promising strategy
for improving utilization efficiency and reducing adverse effects caused by conventional …

Benzimidazoles, the important scaffold of various biologically important molecules, can be
synthesized using metal catalyzed and metal-free methodologies. Recently, metal-free …

Lapatinib (LTP) commercially available as lapatinib ditosylate (LTP-DTS) salt is the only
drug approved for the treatment of HER-positive metastatic breast cancer. A low and pH …

Chromoblastomycosis (CBM) is a neglected human implantation mycosis caused by several
dematiaceous fungal species. Currently available therapy is usually associated with …

BX795 is an emerging drug candidate that has shown a lot of promise as a next-generation
non-nucleoside antiviral agent for the topical treatment of herpes simplex virus type-1 (HSV …

Fenbendazole (FBZ) is a broad-spectrum anthelmintic administered orally to ruminants;
nevertheless, its poor water solubility has been the main limitation to reaching satisfactory …

Pazopanib hydrochloride (PAZ) displays strong intermolecular interaction in its crystal lattice
structure, limiting its solubility and dissolution. The development of lipid-based formulations …

In this work, the co-amorphization approach was applied to flubendazole (FluBZ), resulting
in the formation of two novel solid forms of FluBZ with l-phenylalanine (Phe) and l-tryptophan …

Abstract Active Pharmaceutical Ingredient-Ionic liquids (API-ILs) have the potential to
improve the bioavailability of BCS Class IV Drugs. However, the problematic physical …