The conversion of acetylcholine binding into ion conduction across the membrane is
becoming more clearly understood in terms of the structure of the receptor and its transitions …

The formation of a disulfide bond between adjacent cysteine residues is accompanied by
the formation of a tight turn of the protein backbone. In nearly 90% of the structures analyzed …

We have determined the crystal structure at 1.8 Å resolution of a complex of α-bungarotoxin
with a high affinity 13-residue peptide that is homologous to the binding region of the α …

To understand how snake neurotoxins interact with nicotinic acetylcholine receptors, we
have elaborated an experimentally based model of the α–cobratoxin–α7 receptor complex …

The peptide gp41659-671 (ELLELDKWASLWN) comprises the entire epitope for one of the
three known antibodies capable of neutralizing a broad spectrum of primary HIV-1 isolates …

Alzheimer's disease (AD) is the most common cause of senile dementia and one of the
greatest medical, social, and economic challenges. According to a dominant theory, amyloid …

We report a new, higher resolution NMR structure of α-bungarotoxin that defines the
structure-determining disulfide core and β-sheet regions. We further report the NMR …

The structure of a peptide corresponding to residues 182–202 of the acetylcholine receptor
α1 subunit in complex with α-bungarotoxin was solved using NMR spectroscopy. The …

Nuclear magnetic resonance (NMR) is a very powerful tool for determining the boundaries of
peptide epitopes recognized by antibodies. NMR can be used to study antibodies in …

The α subunit of the nicotinic acetylcholine receptor (AChR) from Torpedo electric organ and
mammalian muscle contains high affinity binding sites for α-bungarotoxin and for …