Synthesis and characterization of Fe (III), Pd (II) and Cu (II)-thiazole complexes; DFT, pharmacophore modeling, in-vitro assay and DNA binding studies

AM Abu-Dief, NM El-Metwaly, SO Alzahrani… - Journal of Molecular …, 2021 - Elsevier
New pharmacologically active complexes were prepared from Pd (II), Fe (III), and Cu (II) ions
with 2-amino-6-oxo-3-(piperidinylamidino)-4-(4methoxyphenyl)-6, 7-dihydro-pyrano [2, 3-d] …

From body art to anticancer activities: perspectives on medicinal properties of henna

R Pradhan, P Dandawate, A Vyas, S Padhye… - Current drug …, 2012 - ingentaconnect.com
Nature has been a rich source of therapeutic agents for thousands of years and an
impressive number of modern drugs have been isolated from natural sources based on the …

Structural inspection for novel Pd (II), VO (II), Zn (II) and Cr (III)-azomethine metal chelates: DNA interaction, biological screening and theoretical treatments

FS Aljohani, AM Abu-Dief, RM El-Khatib… - Journal of Molecular …, 2021 - Elsevier
An alternative sequence of bioactive series, using novel Schiff base derivative (1-Quinolin-8-
yliminomethyl-naphthalen-2-ol), was produced (HNQ). Elements analysis, molar …

New series of thiazole derivatives: synthesis, structural elucidation, antimicrobial activity, molecular modeling and MOE docking

I Althagafi, N El-Metwaly, TA Farghaly - Molecules, 2019 - mdpi.com
Based on the extensive biological activities of thiazole derivatives against different types of
diseases, we are interested in the effective part of many natural compounds, so we …

Optimization for synthesized quinoline-based Cr3+, VO2+, Zn2+ and Pd2+ complexes: DNA interaction, biological assay and in-silico treatments for verification

HA Al-Abdulkarim, RM El-khatib, FS Aljohani… - Journal of Molecular …, 2021 - Elsevier
A novel momonuclear metal chelates were derived from Zn (II), Pd (II), VO (II) and Cr (III) ions
with azomethine (BSQ)[BSQ= 4-Bromo-2-(quinolin-8-yliminomethyl)-phenol] ligand. The …

Novel organoselenium-based N-mealanilic acid and its zinc (II) chelate: Catalytic, anticancer, antimicrobial, antioxidant, and computational assessments

S Shaaban, MSS Adam, NM El-Metwaly - Journal of Molecular Liquids, 2022 - Elsevier
Herein we report the synthesis of two novel Zn (II)-complexes (Zn (LgSe) 2 and Zn (Lg) 2)
starting from 4-((4-(methylselanyl) phenyl) amino)-4-oxobut-2-enoic acid (HLgSe) and 4-oxo …

Structural, conformational and therapeutic studies on new thiazole complexes: drug-likeness and MOE-simulation assessments

AM Abu-Dief, NM El-Metwaly, SO Alzahrani… - Research on Chemical …, 2021 - Springer
A series of new complexes derived from Pd (II), Cu (II) and Fe (III) ions reacted with thiazole
derivative (HL, CPTP) was prepared. Structures of all new compounds were characterized …

Transition metal complexes of 6‐mercaptopurine: Characterization, Theoretical calculation, DNA‐Binding, molecular docking, and anticancer activity

AA Sharfalddin, AH Emwas, M Jaremko… - Applied …, 2021 - Wiley Online Library
6‐mercaptopurine (6‐MP) is used for treating various cancers and autoimmune disorders. A
few examples of transition metal complexes of 6‐MP have been shown to enhance its …

Synthesis, characterization and antifungal activity of a series of manganese (II) and copper (II) complexes with ligands derived from reduced N, N′-O-phenylenebis …

S Belaid, A Landreau, S Djebbar… - Journal of Inorganic …, 2008 - Elsevier
A series of manganese (II) and copper (II) complexes with reduced Schiff bases derived from
o-phenylenediamine has been prepared and characterized by elemental analysis, TG …

Elucidating of new hydrazide-based complexes derived from Pd (II), Cu (II) and Cd (II) ions: studies concerning spectral, DFT, Hirshfeld-crystal, biological screening …

O Alaysuy, HM Abumelha, A Alsoliemy… - Journal of Molecular …, 2022 - Elsevier
A new hydrazide ligand (HL) was characterized to be used for synthesis of some bivalent
complexes via a green approach that free from hazard solvents. All synthesizes were …