The role of the immune microenvironment in bone, cartilage, and soft tissue regeneration: from mechanism to therapeutic opportunity

Y Xiong, BB Mi, Z Lin, YQ Hu, L Yu, KK Zha… - Military Medical …, 2022 - Springer
Bone, cartilage, and soft tissue regeneration is a complex spatiotemporal process recruiting
a variety of cell types, whose activity and interplay must be precisely mediated for effective …

Peripheral nerve injury treatments and advances: one health perspective

B Lopes, P Sousa, R Alvites, M Branquinho… - International journal of …, 2022 - mdpi.com
Peripheral nerve injuries (PNI) can have several etiologies, such as trauma and iatrogenic
interventions, that can lead to the loss of structure and/or function impairment. These …

Clinical trials based on mesenchymal stromal cells are exponentially increasing: where are we in recent years?

U Galderisi, G Peluso, G Di Bernardo - Stem cell reviews and reports, 2022 - Springer
Mesenchymal stromal cells (MSCs), present in the stromal component of several tissues,
include multipotent stem cells, progenitors, and differentiated cells. MSCs have quickly …

Mesenchymal stem cell-derived secretome: a potential therapeutic option for autoimmune and immune-mediated inflammatory diseases

G Műzes, F Sipos - Cells, 2022 - mdpi.com
Immune-mediated inflammatory diseases (IMIDs) encompass several entities such as
“classic” autoimmune disorders or immune-mediated diseases with autoinflammatory …

Adult mesenchymal stem cells and their exosomes: Sources, characteristics, and application in regenerative medicine

M Maqsood, M Kang, X Wu, J Chen, L Teng, L Qiu - Life sciences, 2020 - Elsevier
Human mesenchymal stem cells (MSCs) have become a hot topic in the development of cell
therapies and bioengineering. All kinds of MSCs are genomic stable and have the self …

The therapeutic potential of mesenchymal stromal cells for regenerative medicine: current knowledge and future understandings

M Merimi, R El-Majzoub, L Lagneaux… - Frontiers in Cell and …, 2021 - frontiersin.org
In recent decades, research on the therapeutic potential of progenitor cells has advanced
considerably. Among progenitor cells, mesenchymal stromal cells (MSCs) have attracted …

[HTML][HTML] New strategies of neurodegenerative disease treatment with extracellular vesicles (EVs) derived from mesenchymal stem cells (MSCs)

CP Palanisamy, JJ Pei, P Alugoju, NVA Anthikapalli… - Theranostics, 2023 - ncbi.nlm.nih.gov
Neurodegenerative diseases are characterized by the progressive loss of neurons and
intricate interactions between different cell types within the affected regions. Reliable …

Therapeutic applications of adipose cell-free derivatives: a review

Y Cai, J Li, C Jia, Y He, C Deng - Stem Cell Research & Therapy, 2020 - Springer
Background Adipose-derived stem cells (ADSCs) have become one of the most utilized
adult stem cells due to their abundance and accessibility. Recent studies have shown that …

Emergence of the stem cell secretome in regenerative engineering

L Daneshmandi, S Shah, T Jafari, M Bhattacharjee… - Trends in …, 2020 - cell.com
The secretome is defined as the set of molecules and biological factors that are secreted by
cells into the extracellular space. In the past decade, secretome-based therapies have …

Immunomodulatory mechanisms and therapeutic potential of mesenchymal stem cells

G Yang, X Fan, Y Liu, P Jie, M Mazhar, Y Liu… - Stem Cell Reviews and …, 2023 - Springer
Mesenchymal stem cells (MSCs) are regarded as highly promising cells for allogeneic cell
therapy, owing to their multipotent nature and ability to display potent and varied functions in …