Interferon-gamma (IFNγ) is a central regulator of the immune response and signals via the
Janus Activated Kinase (JAK)-Signal Transducer and Activator of Transcription (STAT) …

Intracellular degradation by autophagy plays a role in the maintenance of cellular
homeostasis under normal conditions and during periods of cellular stress. Autophagy has …

Major histocompatibility complex (MHC) class II molecules present products of lysosomal
proteolysis to CD4+ T cells. Although extracellular antigen uptake is considered to be the …

Magnetic hyperthermia (MH) harnesses the heat‐releasing properties of superparamagnetic
iron oxide nanoparticles (SPIONs) and has potential to stimulate immune activation in the …

Lysosomal exocytosis is a Ca 2+-regulated mechanism that involves proteins responsible
for cytoskeletal attachment and fusion of lysosomes with the plasma membrane. However …

Cancer vaccine has been considered as a promising immunotherapy by inducing specific
anti‐tumor immune response. Rational vaccination at suitable time to efficiently present …

Background Reactive oxygen species are produced in a highly localized and specific
pattern in biological stress responses. The present review examines the redox regulatory …

The immunopeptidome is the repertoire of peptides bound and presented by the MHC class
I, class II, and non-classical molecules. The peptides are produced by the degradation of …

The effectiveness of T-cell-mediated immunotherapy of cancer depends on both an optimal
immunostimulatory context of the therapy and the proper selection with respect to quality …

CD4+ T cells have a major role in regulating immune responses. They are activated by
recognition of peptides mostly generated from exogenous antigens through the major …