The development of high-throughput RNA structure profiling methods in the past decade has
greatly facilitated our ability to map and characterize different aspects of RNA structures …

The Medical Research We have investigated the over-production of seven membrane
proteins in Council Laboratory of an Escherichia coli–bacteriophage T7 RNA polymerase …

Several of the thousands of human long non-coding RNAs (lncRNAs) have been
functionally characterized,,,; however, potential roles for lncRNAs in somatic tissue …

The localization of mRNAs to subcellular compartments provides a mechanism for
regulating gene expression with exquisite temporal and spatial control. Recent studies …

Gene expression is finely regulated at the post-transcriptional level. Features of the
untranslated regions of mRNAs that control their translation, degradation and localization …

Long-lasting forms of synaptic plasticity and memory are dependent on new protein
synthesis. Recent advances obtained from genetic, physiological, pharmacological, and …

RNA transport is an important and fundamental event for local protein synthesis, especially
in neurons. RNA is transported as large granules, but little is known about them. Here, we …

In eukaryotic cells, a multitude of RNA-binding proteins play key roles in the
posttranscriptional regulation of gene expression. Characterization of these proteins has led …

Germ cells play a unique role in gamete production, heredity and evolution. Therefore, to
understand the mechanisms that specify germ cells is a central challenge in developmental …

Post-transcriptional processes have a central role in the regulation of eukaryotic gene
expression. Although it has been known for a long time that these processes are functionally …