Metagenomics and metabolomics approaches in the study of Candida albicans colonization of host niches: a framework for finding microbiome-based antifungal …

M Delavy, N Sertour, C d'Enfert, ME Bougnoux - Trends in Microbiology, 2023 - cell.com
In silico and experimental approaches have allowed an ever-growing understanding of the
interactions within the microbiota. For instance, recently acquired data have increased …

Creating mini-pregnancy models in vitro with clinical perspectives

JY Park, H Lim, J Qin, LP Lee - EBioMedicine, 2023 - thelancet.com
During the last decade, organs-on-chips or organoids microphysiological analysis platforms
(MAP) have garnered attention in the practical applications of disease models, drug …

Human organoid systems in modeling reproductive tissue development, function, and disease

S Haider, AG Beristain - Human Reproduction, 2023 - academic.oup.com
Research focused on human reproductive biology has primarily relied upon clinical samples
affording mainly descriptive studies with limited implementation of functional or mechanistic …

Modelling host–microbiome interactions in organ-on-a-chip platforms

YC Shin, N Than, S Min, W Shin, HJ Kim - Nature Reviews …, 2024 - nature.com
The human microbiome orchestrates a variety of metabolic, immunological and regulatory
functions in health and disease. However, experimentally dissecting host–microbiome …

Organ-on-a-chip: future of female reproductive pathophysiological models

ZM Deng, FF Dai, RQ Wang, HB Deng, TL Yin… - Journal of …, 2024 - Springer
The female reproductive system comprises the internal and external genitalia, which
communicate through intricate endocrine pathways. Besides secreting hormones that …

[HTML][HTML] Host-microbiome interactions in distinct subsets of preterm labor and birth

J Galaz, R Romero, JM Greenberg, KR Theis… - Iscience, 2023 - cell.com
Preterm birth, the leading cause of perinatal morbidity, often follows premature labor, a
syndrome whose prevention remains a challenge. To better understand the relationship …

Review on new approach methods to gain insight into the feto-maternal interface physiology

R Menon, LJ Muglia, LH Levin - Frontiers in Medicine, 2023 - frontiersin.org
Non-human animals represent a large and important feature in the history of biomedical
research. The validity of their use, in terms of reproducible outcomes and translational …

Group B streptococcal infections in pregnancy and early life

G Manuel, J Twentyman, K Noble… - Clinical Microbiology …, 2024 - journals.asm.org
Bacterial infections with Group B Streptococcus (GBS) are an important cause of adverse
outcomes in pregnant individuals, neonates, and infants. GBS is a common commensal in …

Fetal membranes exhibit similar nutrient transporter expression profiles to the placenta

RCV Lintao, AK Kammala, N Vora, JL Yaklic, R Menon - Placenta, 2023 - Elsevier
Introduction During pregnancy, the growth of the fetus is supported by the exchange of
nutrients, waste, and other molecules between maternal and fetal circulations in the utero …

Beyond 2D: Novel biomaterial approaches for modeling the placenta

SG Zambuto, AK Scott, ML Oyen - Placenta, 2024 - Elsevier
This review considers fully three-dimensional biomaterial environments of varying
complexity as these pertain to research on the placenta. The developments in placental cell …