Combining stem cells with biomaterial scaffolds serves as a promising strategy for
engineering tissues for both in vitro and in vivo applications. This updated review details …

Abstract Three-dimensional (3D) organoids derived from pluripotent or adult tissue stem
cells seem to possess excellent potential for studying development and disease …

Recent advances in induced pluripotent stem cell (iPSC) technology have paved the way for
the production of patient-specific neurons that are ideal for autologous cell replacement for …

Gene correction is a valuable strategy for treating inherited retinal degenerative diseases, a
major cause of irreversible blindness worldwide. Single gene defects cause the majority of …

Neuroretinal diseases are the predominant cause of irreversible blindness worldwide,
mainly due to photoreceptor loss. Currently, there are no radical treatments to fully reverse …

Applying scaffolds as a bed to enhance cell proliferation and even differentiation is one of
the treatment of retina diseases such as age-related macular degeneration (AMD) which …

The development of effective tissue engineering materials requires careful consideration of
several properties beyond biocompatibility, including permeability and mechanical stiffness …

Subretinal delivery of stem cell-derived retinal cells as a strategy to treat retinal degenerative
blindness holds great promise. Currently, two clinical trials are underway in which human …

Permanent deficits that occur in memory, sensation, and cognition can result from central
nervous system (CNS) trauma that causes dysfunction and/or unregulated CNS …

As a constituent of blood-retinal barrier and retinal outer segment (ROS) scavenger, retinal
pigmented epithelium (RPE) is fundamental to normal function of retina. Malfunctioning of …