Ionic liquids (ILs), due to their inherent structural tunability, outstanding miscibility behavior,
and excellent electrochemical properties, have attracted significant research attention in the …

Non-steroidal anti-inflammatory drugs (NSAIDs) are among the most common class of drugs
utilized for a variety of disorders, including headaches, pain states, fever, and other common …

Worsening kidney function (WKF) is common in patients with acute heart failure (AHF)
syndromes. Although WKF has traditionally been associated with worse outcomes on a …

Five new pyridazine scaffolds were synthesized and assessed for their inhibitory potential
against both cyclooxygenase-1 (COX-1) and cyclooxygenase-2 (COX-2) compared with …

Ketoprofen (KTF) and ketorolac (KTL) are among the most primarily used non-steroidal anti-
inflammatory drugs (NSAIDs) in humans to alleviate moderate pain and to treat …

Indomethacin (INDO) is an NSAID with remarkable efficacy and widespread utilization for
alleviating pain. Nevertheless, renal function impairment is an adverse reaction linked to …

Background Opioids are commonly prescribed for postoperative pain, but may lead to
prolonged use and addiction. Diabetes impairs nerve function, complicates pain …

Age-related alterations of the kidneys were found at microscopic and macroscopic levels of
the cell. These changes lead to a reduced renal reserve and subsequently to an increased …

A novel therapeutic approach combining acupuncture and diclofenac sodium (DS)
administration was established for the potential treatment for rheumatoid arthritis (RA). DS is …

The protopine alkaloids are widely distributed within the opium poppy family and have a
wide range of pharmacological effects. MPTA is a product of the protopine total alkaloids …