Use of brain biomechanical models for monitoring impact exposure in contact sports

S Ji, M Ghajari, H Mao, RH Kraft… - Annals of Biomedical …, 2022 - Springer
Head acceleration measurement sensors are now widely deployed in the field to monitor
head kinematic exposure in contact sports. The wealth of impact kinematics data provides …

An analytical review of the numerical methods used for finite element modeling of traumatic brain injury

JS Giudice, W Zeng, T Wu, A Alshareef… - Annals of biomedical …, 2019 - Springer
Dozens of finite element models of the human brain have been developed for providing
insight into the mechanical response of the brain during impact. Many models used in …

Finite element methods in human head impact simulations: a review

A Madhukar, M Ostoja-Starzewski - Annals of biomedical engineering, 2019 - Springer
Head impacts leading to traumatic brain injury (TBI) present a major health risk today,
projected to become the third leading cause of death by 2020. While finite element (FE) …

Explicit modeling of white matter axonal fiber tracts in a finite element brain model

T Wu, A Alshareef, JS Giudice, MB Panzer - Annals of biomedical …, 2019 - Springer
Many human brain finite element (FE) models lack mesoscopic (~ 1 mm) white matter
structures, which may limit their capability in predicting TBI and assessing tissue-based …

Embedded axonal fiber tracts improve finite element model predictions of traumatic brain injury

M Hajiaghamemar, T Wu, MB Panzer… - … and modeling in …, 2020 - Springer
With the growing rate of traumatic brain injury (TBI), there is an increasing interest in
validated tools to predict and prevent brain injuries. Finite element models (FEM) are …

In vivo estimates of axonal stretch and 3D brain deformation during mild head impact

AK Knutsen, AD Gomez, M Gangolli, WT Wang… - Brain multiphysics, 2020 - Elsevier
The rapid deformation of brain tissue in response to head impact can lead to traumatic brain
injury. In vivo measurements of brain deformation during non-injurious head impacts are …

The dynamics of concussion: mapping pathophysiology, persistence, and recovery with causal-loop diagramming

ES Kenzie, EL Parks, ED Bigler, DW Wright… - Frontiers in …, 2018 - frontiersin.org
Despite increasing public awareness and a growing body of literature on the subject of
concussion, or mild traumatic brain injury, an urgent need still exists for reliable diagnostic …

MR Imaging of Human Brain Mechanics In Vivo: New Measurements to Facilitate the Development of Computational Models of Brain Injury

PV Bayly, A Alshareef, AK Knutsen, K Upadhyay… - Annals of biomedical …, 2021 - Springer
Computational models of the brain and its biomechanical response to skull accelerations
are important tools for understanding and predicting traumatic brain injuries (TBIs) …

Displacement-and strain-based discrimination of head injury models across a wide range of blunt conditions

W Zhao, S Ji - Annals of biomedical engineering, 2020 - Springer
Successful validation of a head injury model is critical to ensure its biofidelity. However,
there is an ongoing debate on what experimental data are suitable for model validation …

Multi-scale white matter tract embedded brain finite element model predicts the location of traumatic diffuse axonal injury

M Hajiaghamemar, SS Margulies - Journal of Neurotrauma, 2021 - liebertpub.com
Finite element models (FEMs) are used increasingly in the traumatic brain injury (TBI) field to
provide an estimation of tissue responses and predict the probability of sustaining TBI after a …