Heterogeneity and plasticity of epithelial–mesenchymal transition (EMT) in cancer metastasis: Focusing on partial EMT and regulatory mechanisms

D Li, L Xia, P Huang, Z Wang, Q Guo, C Huang… - Cell …, 2023 - Wiley Online Library
Epithelial–mesenchymal transition (EMT) or mesenchymal–epithelial transition (MET) plays
critical roles in cancer metastasis. Recent studies, especially those based on single‐cell …

[HTML][HTML] Targeted therapy and mechanisms of drug resistance in breast cancer

B Kinnel, SK Singh, G Oprea-Ilies, R Singh - Cancers, 2023 - mdpi.com
Simple Summary Internationally, in women, breast cancer (BC) is the most common cancer
type and is the leading cause of cancer-related death. There are two main histological …

[HTML][HTML] Cancer-associated fibroblast heterogeneity in axillary lymph nodes drives metastases in breast cancer through complementary mechanisms

F Pelon, B Bourachot, Y Kieffer, I Magagna… - Nature …, 2020 - nature.com
Although fibroblast heterogeneity is recognized in primary tumors, both its characterization
in and its impact on metastases remain unknown. Here, combining flow cytometry …

[HTML][HTML] MicroRNAs in regulation of triple-negative breast cancer progression

D Piasecka, M Braun, R Kordek, R Sadej… - Journal of cancer …, 2018 - Springer
Purpose Dysregulation of miRNA profile has been associated with a broad spectrum of
cellular processes underlying progression of various human malignancies. Increasing …

[HTML][HTML] Plasma cell-free DNA (cfDNA) as a predictive and prognostic marker in patients with metastatic breast cancer

D Fernandez-Garcia, A Hills, K Page… - Breast Cancer …, 2019 - Springer
Background Breast cancer (BC) is the most common cancer in women, and despite the
introduction of new screening programmes, therapies and monitoring technologies, there is …

[HTML][HTML] LncRNA MAGI2-AS3 is regulated by BRD4 and promotes gastric cancer progression via maintaining ZEB1 overexpression by sponging miR-141/200a

D Li, J Wang, M Zhang, X Hu, J She, X Qiu… - … Therapy-Nucleic Acids, 2020 - cell.com
Long non-coding RNAs (lncRNAs) play critical roles in tumorigenesis and tumor
progression. However, the biological function of most lncRNAs remains unknown in human …

[HTML][HTML] The m6A methyltransferase METTL3 controls epithelial-mesenchymal transition, migration and invasion of breast cancer through the MALAT1/miR-26b …

C Zhao, X Ling, Y Xia, B Yan, Q Guan - Cancer Cell International, 2021 - Springer
Background Previous studies have revealed the key functions of N6-methyladenosine (m6A)
modification in breast cancer (BC). MALAT1 as a highly m6A modified lncRNA associated …

[HTML][HTML] The epithelial-to-mesenchymal transition in breast cancer: focus on basal-like carcinomas

M Fedele, L Cerchia, G Chiappetta - Cancers, 2017 - mdpi.com
Breast cancer is a heterogeneous disease that is characterized by a high grade of cell
plasticity arising from the contribution of a diverse range of factors. When combined, these …

[HTML][HTML] MicroRNAs involved in carcinogenesis, prognosis, therapeutic resistance, and applications in human triple-negative breast cancer

L Ding, H Gu, X Xiong, H Ao, J Cao, W Lin, M Yu, J Lin… - Cells, 2019 - mdpi.com
Triple-negative breast cancer (TNBC) is the most aggressive, prevalent, and distinct subtype
of breast cancer characterized by high recurrence rates and poor clinical prognosis, devoid …

[HTML][HTML] Chronic stress promotes EMT-mediated metastasis through activation of STAT3 signaling pathway by miR-337-3p in breast cancer

P Du, H Zeng, Y Xiao, Y Zhao, B Zheng, Y Deng… - Cell death & …, 2020 - nature.com
Chronic stress could induce cancer metastasis by constant activation of the sympathetic
nervous system, while cellular mechanism remains obscure. The aim of this research is to …