[HTML][HTML] Lipid metabolism and identification of biomarkers in asthma by lipidomic analysis

T Jiang, L Dai, P Li, J Zhao, X Wang, L An, M Liu… - … et Biophysica Acta (BBA …, 2021 - Elsevier
Background Lipids participate in many important biological functions through energy
storage, material transport, signal transduction, and molecular recognition processes …

Molecular determinants as therapeutic targets in cancer chemotherapy: an update

T Haider, R Tiwari, SP Vyas, V Soni - Pharmacology & therapeutics, 2019 - Elsevier
It is well known that cancer cells are heterogeneous in nature and very distinct from their
normal counterparts. Commonly these cancer cells possess different and complementary …

Long-term chronic food-derived arsenic exposure induce the urinary system metabolic dysfunction in mice

Z Huang, L Guo, X Chen, J Sun, Y Ye, L Sheng… - Science of the Total …, 2023 - Elsevier
The consumption of rice contaminated with arsenic on a long-term basis has emerged as a
pressing public health issue of global significance. Arsenic-induced urinary injury …

Lipidomics in ulcerative colitis reveal alteration in mucosal lipid composition associated with the disease state

J Diab, T Hansen, R Goll, H Stenlund… - Inflammatory Bowel …, 2019 - academic.oup.com
Background The onset of ulcerative colitis (UC) is associated with alterations in lipid
metabolism and a disruption of the balance between pro-and anti-inflammatory molecules …

Response surface methodology and artificial neural network-based modeling and optimization of phosphatidylserine targeted nanocarriers for effective treatment of …

T Haider, V Soni - Journal of Drug Delivery Science and Technology, 2022 - Elsevier
This study aimed to develop and evaluate phosphatidylserine (PS)-targeted nanoparticles
for efficient delivery of methotrexate to tumor sites. Therefore, methotrexate-loaded …

Lycium barbarum polysaccharides ameliorate canine acute liver injury by reducing oxidative stress, protecting mitochondrial function, and regulating metabolic …

J Huang, Y Bai, W Xie, R Wang, W Qiu, S Zhou… - Journal of Zhejiang …, 2023 - Springer
The development of acute liver injury can result in liver cirrhosis, liver failure, and even liver
cancer, yet there is currently no effective therapy for it. The purpose of this study was to …

Lipid-encapsulated siRNA for hepatocyte-directed treatment of advanced liver disease

MM Woitok, ME Zoubek, D Doleschel, M Bartneck… - Cell Death & …, 2020 - nature.com
Lipid-based RNA nanocarriers have been recently accepted as a novel therapeutic option in
humans, thus increasing the therapeutic options for patients. Tailored nanomedicines will …

Metabolomics identifies metabolite markers in plasma and extracellular vesicles within plasma in patients with asthma

CJ Chang, QW Ma, TL Li, JA Liu, CH Hsieh, L Chen - Clinica Chimica Acta, 2025 - Elsevier
Background Plasma and extracellular vesicles (EVs) derived from plasma are important
sources of information regarding individual health. Metabolomic analysis of plasma and EVs …

Effect of simulated microgravity on metabolism of HGC-27 gastric cancer cells

ZY Chen, N Jiang, S Guo, BB Li… - Oncology …, 2020 - spandidos-publications.com
The understanding into the pathogenesis and treatment of gastric cancer has improved in
recent years; however, a number of limitations have delayed the development of effective …

Advances in understanding and in multi-disciplinary methodology used to assess lipid regulation of signalling cascades from the cancer cell plasma membrane

C Soteriou, AC Kalli, SD Connell, AII Tyler… - Progress in Lipid …, 2021 - Elsevier
The lipid bilayer is a functional component of cells, forming a stable platform for the initiation
of key biological processes, including cell signalling. There are distinct changes in the lipid …