The emergence of form and function during mammalian embryogenesis is a complex
process that involves multiple regulatory levels. The foundations of the body plan are laid …

Cells have an intrinsic ability to self-assemble and self-organize into complex and functional
tissues and organs. By taking advantage of this ability, embryoids, organoids and …

The human embryo undergoes morphogenetic transformations following implantation into
the uterus, but our knowledge of this crucial stage is limited by the inability to observe the …

Remodelling of the human embryo at implantation is indispensable for successful
pregnancy. Yet it has remained mysterious because of the experimental hurdles that beset …

Following implantation, the human embryo undergoes major morphogenetic transformations
that establish the future body plan. While the molecular events underpinning this process …

The evolution of embryo models | Nature Methods Skip to main content Thank you for
visiting nature.com. You are using a browser version with limited support for CSS. To obtain …

Transformation of pluripotent epiblast cells into a cup-shaped epithelium as the mouse
blastocyst implants is a poorly understood and yet key developmental step. Studies of …

INTRODUCTION Gastrulation is a landmark event in development that involves a complex
series of molecular, physical, and energetic remodeling transitions in early embryogenesis …

In mammals, all somatic development originates from lineage segregation in early embryos.
However, the dynamics of transcriptomes and epigenomes acting in concert with initial cell …

Embryo implantation into the uterus marks a key transition in mammalian development. In
mice, implantation is mediated by the trophoblast and is accompanied by a morphological …