Suppressing inflammation has been the primary focus of therapies in autoimmune rheumatic
diseases (AIRDs), including rheumatoid arthritis and systemic lupus erythematosus …

Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by
neovascularization, immune cell infiltration, and synovial hyperplasia, which leads to …

CD38 has emerged as a potential therapeutic target for patients with systemic lupus
erythematosus (SLE) but it is not known whether CD38 alters CD4+ T cell function. Using …

Systemic lupus erythematosus (SLE) is a chronic autoimmune disorder in which pathogenic
abnormalities within both the innate and adaptive immune response have been described …

Cardiovascular disease (CVD) is a leading cause of mortality in patients with juvenile-onset
systemic lupus erythematosus (JSLE) associated with atherosclerosis. The interplay …

Regulatory T cells (Tregs) suppress pro-inflammatory conventional T cell (Tconv) responses.
As lipids impact cell signaling and function, we compare the lipid composition of CD4+ …

Systemic lupus erythematosus (SLE) is an autoimmune disease in which the immune
system attacks its own tissues and organs. However, the causes of SLE remain unknown …

Vitamin D3 is an essential micronutrient mediating pleiotropic effects in multiple tissues and
cell types via its metabolite 1α, 25-dihydroxyvitamin D3 (1, 25 (OH) 2D3), which activates the …

Flavour precursors are the basis of meat flavour, and their metabolism is regulated by a
variety of enzymes. Thus, it is of great significance to identify the key genes related to meat …

The field of sterol and oxysterol biology in lung disease has recently gained attention,
revealing a unique need for sterol uptake and metabolism in the lung. The presence of …