Polymerization of actin filaments against membranes produces force for numerous cellular
processes, such as migration, morphogenesis, endocytosis, phagocytosis and organelle …

Actin remodeling is at the heart of the response of cells to external or internal stimuli,
allowing a variety of membrane protrusions to form. Fifteen years ago, tunneling nanotubes …

Filopodia are dynamic cell surface protrusions used for cell motility, pathogen infection, and
tissue development. The molecular mechanisms determining how and where filopodia grow …

Cells use the actin cytoskeleton for many of their functions, including their division,
adhesion, mechanosensing, endo-and phagocytosis, migration, and invasion. Actin bundles …

Filopodia are dynamic, narrow, plasma membrane protrusions filled with bundled actin
filaments. Fresh actin monomers are incorporated at the tips furthest away from the cell …

Fascin actin-bundling protein 1 (FSCN1) is a highly conserved actin-bundling protein that
cross links F-actin microfilaments into tight, parallel bundles. Elevated FSCN1 levels have …

Filopodia are actin-rich membrane protrusions essential for cell morphogenesis, motility,
and cancer invasion. How cells control filopodium initiation on the plasma membrane …

According to the cellular actin dynamics paradigm, filaments grow at their barbed ends and
depolymerize predominantly from their pointed ends to form polar structures and do …

Simple Summary Cell migration is an essential biological process that regulates both
development and diseases, such as cancer metastasis. Therefore, understanding the factors …

Abstract Changes in cell morphology require the dynamic remodeling of the actin
cytoskeleton. Calcium fluxes have been suggested as an important signal to rapidly relay …