[HTML][HTML] Biology and pathogenesis of Acanthamoeba

R Siddiqui, NA Khan - Parasites & vectors, 2012 - Springer
Acanthamoeba is a free-living protist pathogen, capable of causing a blinding keratitis and
fatal granulomatous encephalitis. The factors that contribute to Acanthamoeba infections …

Acanthamoeba keratitis: an emerging disease gathering importance worldwide?

J Lorenzo-Morales, CM Martín-Navarro… - Trends in …, 2013 - cell.com
Acanthamoeba keratitis (AK) is increasingly being recognized as a severe sight-threatening
ocular infection worldwide. Although contact lens wear is the leading risk factor for AK …

[PDF][PDF] Acanthamoeba

NA Khan - Biology and pathogenesis, 2009 - caister.com
1. A host for viruses 2. A host for yeast 3. A host for protists 4. Acanthamoeba and bacteria
interactions 5. Is Acanthamoebaan evolutionary ancestor of macrophages? 6 …

[HTML][HTML] Osteoarthritis and toll-like receptors: when innate immunity meets chondrocyte apoptosis

G Barreto, M Manninen, K K. Eklund - Biology, 2020 - mdpi.com
Osteoarthritis (OA) has long been viewed as a degenerative disease of cartilage, but
accumulating evidence indicates that inflammation has a critical role in its pathogenesis. In …

[HTML][HTML] Drug Discovery against Acanthamoeba Infections: Present Knowledge and Unmet Needs

HM Elsheikha, R Siddiqui, NA Khan - Pathogens, 2020 - mdpi.com
Although major strides have been made in developing and testing various anti-
acanthamoebic drugs, recurrent infections, inadequate treatment outcomes, health …

Leishmanicidal activity of α-bisabolol from Tunisian chamomile essential oil

S Hajaji, I Sifaoui, A López-Arencibia… - Parasitology …, 2018 - Springer
Abstract According to the World Health Organization, leishmaniasis is considered as a major
neglected tropical disease causing an enormous impact on global public health. Available …

[HTML][HTML] Programmed cell death in Acanthamoeba castellanii Neff induced by several molecules present in olive leaf extracts

I Sifaoui, A Lopez-Arencibia, CM Martín-Navarro… - PloS one, 2017 - journals.plos.org
Therapy against Acanthamoeba infections such as Granulomatous Amoebic Encephalitis
(GAE) and Acanthamoeba Keratitis (AK), remains as an issue to be solved due to the …

Box Behnken design of siRNA-loaded liposomes for the treatment of a murine model of ocular keratitis caused by Acanthamoeba

GK Zorzi, RS Schuh, VJ Maschio, NT Brazil… - Colloids and Surfaces B …, 2019 - Elsevier
Acanthamoeba keratitis is an ophthalmic disease with no specific treatment that specially
affects contact lens users. The silencing of serine phosphatase (SP) and glycogen …

[HTML][HTML] Antiamoebic Activity of Imidazothiazole Derivatives against Opportunistic Pathogen Acanthamoeba castellanii

N Akbar, MI El-Gamal, BQ Saeed, CH Oh… - Antibiotics, 2022 - mdpi.com
We examined the antiamoebic effect of several imidazothiazole derivatives on
Acanthamoeba castellanii of the T4 genotype. Trypan blue exclusion assays and …

Guanidinium ionic liquid-based surfactants as low cytotoxic extractants: Analytical performance in an in-situ dispersive liquid–liquid microextraction method for …

I Pacheco-Fernández, V Pino, JH Ayala… - … of Chromatography A, 2018 - Elsevier
The IL-based surfactant octylguanidinium chloride (C 8 Gu-Cl) was designed and
synthetized with the purpose of obtaining a less harmful surfactant: containing guanidinium …