What is holding back the development of antiviral metallodrugs? A literature overview and implications for SARS-CoV-2 therapeutics and future viral outbreaks
In light of the Covid-19 outbreak, this review brings together historical and current literature
efforts towards the development of antiviral metallodrugs. Classical compounds such as …
efforts towards the development of antiviral metallodrugs. Classical compounds such as …
Synthesis, spectroscopic, DFT calculations, antimicrobial, cytotoxicity, and DNA binding studies of novel Cu (II), Ni (II), Zn (II), and VO (II) Schiff base complexes based …
LH Abdel‐Rahman… - Applied …, 2022 - Wiley Online Library
The ibuprofen Schiff base ligand (HL)[HL= 2‐(4‐Isobutyl‐phenyl)‐propionic acid (3‐hydroxy‐
naphthalen‐2‐ylmethylene)‐hydrazide] and its Cu (II), Ni (II), Zn (II), and VO (II) chelates …
naphthalen‐2‐ylmethylene)‐hydrazide] and its Cu (II), Ni (II), Zn (II), and VO (II) chelates …
A new palladium (II) complex with ibuprofen: Spectroscopic characterization, DFT studies, antibacterial activities and interaction with biomolecules
This work describes the synthesis, characterization and antibacterial activities of a palladium
(II) complex with ibuprofen (ibu). Elemental and mass spectrometric data (ESI-QTOF-MS) …
(II) complex with ibuprofen (ibu). Elemental and mass spectrometric data (ESI-QTOF-MS) …
Synthesis, crystal structures, DFT studies, antibacterial assays and interaction assessments with biomolecules of new platinum (ii) complexes with adamantane …
AK dos Santos Pereira, CM Manzano… - New Journal of …, 2020 - pubs.rsc.org
Three platinum (II) complexes containing amantadine (atd), rimantadine (rtd) and
memantine (mtn) as ligands were synthesized and characterized by chemical and …
memantine (mtn) as ligands were synthesized and characterized by chemical and …
Synthesis, crystallographic studies, molecular modeling and in vitro biological studies of silver (I) complexes with aminoadamantane ligands
AK dos Santos Pereira, DH Nakahata, CM Manzano… - Polyhedron, 2019 - Elsevier
Silver (I) complexes with amantadine (atd) and memantine (mtn) were synthesized and
characterized. Elemental, thermogravimetric and mass spectrometric analyses indicated a 1 …
characterized. Elemental, thermogravimetric and mass spectrometric analyses indicated a 1 …
[HTML][HTML] Multi-activity tetracoordinated pallado-oxadiazole thiones as anti-inflammatory, anti-Alzheimer, and anti-microbial agents: Structure, stability and bioactivity …
Herein, we report a comparative study based on structure, thermal and solution stability, and
biopotency against lipoxygenase (LOX), butyrylcholinesterase (BChE) and microbes for Pd …
biopotency against lipoxygenase (LOX), butyrylcholinesterase (BChE) and microbes for Pd …
Antiproliferative Activity of Gold (I) N‐Heterocyclic Carbene and triphenylphosphine complexes with ibuprofen derivatives as effective enzyme inhibitors
L Tabrizi, J Romanova - Applied Organometallic Chemistry, 2020 - Wiley Online Library
A series of gold (I) complexes of ligand ibuprofen‐alkynyl (but‐3‐yn‐1‐yl 2‐(4‐
isobutylphenyl) propanoate, LE) with N‐heterocyclic carbene (LC: 1, 3‐dimethylimidazol‐2 …
isobutylphenyl) propanoate, LE) with N‐heterocyclic carbene (LC: 1, 3‐dimethylimidazol‐2 …
Coordination compounds of zinc carboxylates with an unusual benzohydrazide binding mode
T Koksharova, Y Slyvka, O Savchenko… - Journal of Molecular …, 2025 - Elsevier
Two new coordination compounds [Zn (Bhz) 4 (p-OB) 2](1) and [Zn (Bhz) 3][Zn (Bhz) 2 (Fum)
2]. 2H 2 O (2)(Bhz–benzohydrazide, p-OB-p-hydroxybenzoate, Fum-fumarate anions) have …
2]. 2H 2 O (2)(Bhz–benzohydrazide, p-OB-p-hydroxybenzoate, Fum-fumarate anions) have …
Copper (II) and Platinum (II) Naproxenates: Insights on Synthesis, Characterization and Evaluation of Their Antiproliferative Activities
AA Silva, SCL Frajácomo, ÁB Cruz, KE Buglio… - Inorganics, 2023 - mdpi.com
The growth of antibiotic resistance is a matter of worldwide concern. In parallel, cancer
remains one of the main causes of death. In the search for new and improved …
remains one of the main causes of death. In the search for new and improved …
Lanthanum (III) and neodymium (III) complexes with anti-inflammatory drug sulindac: Synthesis, characterization, thermal investigation using coupled techniques TG …
RB Guerra, TF de Campos Fraga-Silva, J Aguiar… - Inorganica Chimica …, 2020 - Elsevier
New lanthanum (III) and neodymium (III) complexes with the anti-inflammatory drug sulindac
(Sul) were synthesized and characterized, and their biological activity was evaluated in vitro …
(Sul) were synthesized and characterized, and their biological activity was evaluated in vitro …