Beyond trial and error: Leveraging advanced software for Therapeutic discovery

V Rustagi, SRR Gupta, A Singh… - Chemical Biology …, 2025 - pubs.thesciencein.org
In drug discovery, efficiency and precision are crucial elements that play pivotal roles in
saving lives, time, and financial resources while pursuing groundbreaking advancements …

Competitive dewetting underlies site-specific binding of general anesthetics to GABA (A) receptors

S Murlidaran, J Hénin, G Brannigan - bioRxiv, 2019 - biorxiv.org
GABA (A) receptors are pentameric ligand-gated ion channels playing a critical role in the
modulation of neuronal excitability. These inhibitory receptors, gated by γ-aminobutyric acid …

Gene Therapy and Editing for the Treatment of Single-Gene Pain Disorders

FH Shah, SJ Kim, J Idrees, M Tariq… - … Strategies and New …, 2021 - benthamdirect.com
It is a well-known reality that genetic variants can alter the pain perception of an individual in
correlation with painless and painful voltage-gated Nachannelopathies for the better …

[PDF][PDF] Competitive dewetting underlies subunit-specific binding of general anesthetics to GABA (A) receptors

S Murlidaran, J Hénin, G Brannigan - 2013 - researchgate.net
GABA (A) receptors are pentameric ligand-gated ion channels playing a critical role in the
modulation of neuronal excitability. These inhibitory receptors, gated by γ-aminobutyric acid …

[引用][C] Comparative studies on the binding site of anesthetics to GABA a receptors using in silico docking methods

S AHN, JY LEE, J SUNG, HJOO KIM, S PARK - 2023 - Centro Regional de Investigaciones …