Past, present, and future of circ RNA s

IL Patop, S Wüst, S Kadener - The EMBO journal, 2019 - embopress.org
Exonic circular RNA s (circ RNA s) are covalently closed RNA molecules generated by a
process named back‐splicing. circ RNA s are highly abundant in eukaryotes, and many of …

Circular RNAs in cell differentiation and development

G Di Timoteo, F Rossi, I Bozzoni - Development, 2020 - journals.biologists.com
In recent years, circular RNAs (circRNAs)–a novel class of RNA molecules characterized by
their covalently closed circular structure–have emerged as a complex family of eukaryotic …

Non-coding RNAs shaping muscle

J Martone, D Mariani, F Desideri… - Frontiers in cell and …, 2020 - frontiersin.org
In 1957, Francis Crick speculated that RNA, beyond its protein-coding capacity, could have
its own function. Decade after decade, this theory was dramatically boosted by the discovery …

Role of virally encoded circular RNAs in the pathogenicity of human oncogenic viruses

J Avilala, D Becnel, R Abdelghani, A Nanbo… - Frontiers in …, 2021 - frontiersin.org
Human oncogenic viruses are a group of important pathogens that etiologically contribute to
at least 12% of total cancer cases in the world. As an emerging class of non-linear regulatory …

Non-canonical functions of splicing factors in RNA metabolism

X Han, Y Lin, XQ Gao, XL Wang - Critical Reviews in Plant …, 2020 - Taylor & Francis
Noncoding RNA (ncRNA), such as microRNA (miRNAs), long ncRNAs (lncRNAs), and
circular RNAs (circRNAs) play roles in plant growth, development, and response to …

Analyses of circRNA expression throughout circadian rhythm reveal a strong link between Cdr1as and light-induced phase shifts in the SCN

A Ivanov, D Mattei, K Radscheit, AC Compagnion… - bioRxiv, 2022 - biorxiv.org
Cdr1as is a conserved circular RNA (circRNA) enriched in the CNS and important for
maintaining brain homeostasis. The loss of Cdr1as results in aberrant synaptic transmission …

[图书][B] A Stress-Responsive circRNA Alters Behavioral, Molecular, and Transcriptional Phenotypes in Mouse Models of Depressive-Like Behavior

VE Lehmann - 2022 - search.proquest.com
Depression is a chronic illness that is pervasive and debilitating. Though we have made
many advances in the study of its molecular underpinnings, the efficacy of treatments for the …

Investigation of cap-independent translation in neuronal differentiation

L Ruhe - 2020 - edoc.hu-berlin.de
Translation initiation is a complex and highly regulated process which involves the assembly
of an elongation competent ribosome on the mRNA. The vast majority of eukaryotic mRNAs …