In recent years, circular RNAs (circRNAs)–a novel class of RNA molecules characterized by their covalently closed circular structure–have emerged as a complex family of eukaryotic …
J Martone, D Mariani, F Desideri… - Frontiers in cell and …, 2020 - frontiersin.org
In 1957, Francis Crick speculated that RNA, beyond its protein-coding capacity, could have its own function. Decade after decade, this theory was dramatically boosted by the discovery …
J Avilala, D Becnel, R Abdelghani, A Nanbo… - Frontiers in …, 2021 - frontiersin.org
Human oncogenic viruses are a group of important pathogens that etiologically contribute to at least 12% of total cancer cases in the world. As an emerging class of non-linear regulatory …
X Han, Y Lin, XQ Gao, XL Wang - Critical Reviews in Plant …, 2020 - Taylor & Francis
Noncoding RNA (ncRNA), such as microRNA (miRNAs), long ncRNAs (lncRNAs), and circular RNAs (circRNAs) play roles in plant growth, development, and response to …
A Ivanov, D Mattei, K Radscheit, AC Compagnion… - bioRxiv, 2022 - biorxiv.org
Cdr1as is a conserved circular RNA (circRNA) enriched in the CNS and important for maintaining brain homeostasis. The loss of Cdr1as results in aberrant synaptic transmission …
Depression is a chronic illness that is pervasive and debilitating. Though we have made many advances in the study of its molecular underpinnings, the efficacy of treatments for the …
Translation initiation is a complex and highly regulated process which involves the assembly of an elongation competent ribosome on the mRNA. The vast majority of eukaryotic mRNAs …