Advances and challenges in small‐molecule DNA aptamer isolation, characterization, and sensor development

H Yu, O Alkhamis, J Canoura, Y Liu… - Angewandte Chemie …, 2021 - Wiley Online Library
Aptamers are short oligonucleotides isolated in vitro from randomized libraries that can bind
to specific molecules with high affinity, and offer a number of advantages relative to …

Electrochemical methods for the analysis of clinically relevant biomolecules

M Labib, EH Sargent, SO Kelley - Chemical reviews, 2016 - ACS Publications
Rapid progress in identifying biomarkers that are hallmarks of disease has increased
demand for high-performance detection technologies. Implementation of electrochemical …

[HTML][HTML] A review on label free biosensors

VR Samuel, KJ Rao - Biosensors and Bioelectronics: X, 2022 - Elsevier
Label-free biosensing has advanced significantly in recent years due to its capacity for quick
and inexpensive bio-detection in small volumes. Additionally, they have developed into lab …

Nucleic acid biosensors: recent advances and perspectives

Y Du, S Dong - Analytical chemistry, 2017 - ACS Publications
The creation of biosensors has given rise to a revolution in many fields like medical and
health, food inspection, environmental monitoring, and so on. The simplicity, convenience …

Small-molecule binding aptamers: Selection strategies, characterization, and applications

A Ruscito, MC DeRosa - Frontiers in chemistry, 2016 - frontiersin.org
Aptamers are single-stranded, synthetic oligonucleotides that fold into 3-dimensional
shapes capable of binding non-covalently with high affinity and specificity to a target …

Electrochemical aptamer-based sensors for food and water analysis: A review

F Li, Z Yu, X Han, RY Lai - Analytica Chimica Acta, 2019 - Elsevier
Global food and water safety issues have prompted the development of highly sensitive,
specific, and fast analytical techniques for food and water analysis. The electrochemical …

[HTML][HTML] Comparative analysis of breast cancer detection using machine learning and biosensors

Y Amethiya, P Pipariya, S Patel, M Shah - Intelligent Medicine, 2022 - Elsevier
Breast cancer is a widely occurring cancer in women worldwide and is related to high
mortality. The objective of this review was to present several approaches to investigate the …

Aptamers in biomedicine: Selection strategies and recent advances

G Ștefan, O Hosu, K De Wael, MJ Lobo-Castañón… - Electrochimica …, 2021 - Elsevier
Aptamers have come in the spotlight as bio-mimetic molecular recognition elements in the
field of biomedicine due to various applications in diagnostics, drug delivery, therapeutics …

Duplexed aptamers: history, design, theory, and application to biosensing

JD Munzar, A Ng, D Juncker - Chemical Society Reviews, 2019 - pubs.rsc.org
Nucleic acid aptamers are single stranded DNA or RNA sequences that specifically bind a
cognate ligand. In addition to their widespread use as stand-alone affinity binding reagents …

Selection and biosensor application of aptamers for small molecules

F Pfeiffer, G Mayer - Frontiers in chemistry, 2016 - frontiersin.org
Small molecules play a major role in the human body and as drugs, toxins, and chemicals.
Tools to detect and quantify them are therefore in high demand. This review will give an …