Ischemic stroke is one of the leading causes of mortality and disability worldwide. However,
there is a current lack of effective therapies available. As the resident macrophages of the …

Aortic aneurysm is an asymptomatic disease with dire outcomes if undiagnosed. Aortic
aneurysm rupture is a significant cause of death worldwide. To date, surgical repair or …

Within the last year, four randomised-controlled clinical trials (RCTs) have been published
comparing intravenous thrombolysis (IVT) with tenecteplase and alteplase in acute …

Autophagy of mitochondria, termed mitophagy, plays an important role in cerebral ischemia-
reperfusion (IR) injury, but the mechanism is not yet clear. Tissue-type plasminogen activator …

Rationale: Hemorrhagic complications represent a major limitation of intravenous
thrombolysis using tPA (tissue-type plasminogen activator) in patients with ischemic stroke …

Stroke is one of the leading causes of death and long-term disability worldwide. More than
80% of strokes are ischemic, caused by an occlusion of cerebral arteries. Without question …

Biomarkers are objective indicators used to assess normal or pathological processes,
evaluate responses to treatment and predict outcomes. Many blood biomarkers already …

A thrombus is a blood clot that forms in the lumen of an artery or vein, restricting blood flow
and causing clinical symptoms. Thrombosis is associated with many life‐threatening …

Residual Fatigue and Cognitive Deficits in Patients After Leucine-Rich Glioma-Inactivated 1
Antibody Encephalitis | Allergy and Clinical Immunology | JAMA Neurology | JAMA Network [Skip …

The constant failure of new neuroprotective therapies for ischemic stroke has partially halted
the search for new therapies in recent years, mainly because of the high investment risk …