The human brain undergoes a prolonged period of cortical development that spans multiple
decades. During childhood and adolescence, cortical development progresses from lower …

Practitioners frequently use diagnostic criteria to identify children with neurodevelopmental
disorders and to guide intervention decisions. These criteria also provide the organising …

In both child and adult psychiatry, empirical evidence has now accrued to suggest that a
single dimension is able to measure a person's liability to mental disorder, comorbidity …

Importance Between-individual variability in brain structure is determined by gene-
environment interactions, possibly reflecting differential sensitivity to environmental and …

Abstract A general psychopathology ('p') factor captures shared variation across mental
disorders. One hypothesis is that poor executive function (EF) contributes to p. Although EF …

The macro-and microstructural architecture of human brain white matter undergoes
substantial alterations throughout development and ageing. Most of our understanding of …

An important advance in understanding and defining mental disorders has been the
development of empirical approaches to mapping dimensions of dysfunction and their …

Background There is considerable interest in a dimensional transdiagnostic approach to
psychiatry. Most transdiagnostic studies have derived factors based only on clinical …

What is the neurobiological basis of human intelligence? The brains of some people seem
to be more efficient than those of others. Understanding the biological foundations of these …

Background Accumulating evidence supports cerebellar involvement in mental disorders,
such as schizophrenia, bipolar disorder, depression, anxiety disorders, and attention …