Procalcitonin (PCT) and C-reactive protein (CRP) are commonly used biomarkers, but their
diagnostic advantage for neonatal early-onset (EOS) or late-onset (LOS) sepsis is …

Fever in children is a common concern for parents and one of the most frequent presenting
complaints in emergency department visits, often involving non-pediatric emergency …

Background Efforts to develop an evidence-based approach to the evaluation and
management of young febrile infants have spanned more than 4 decades. 1 In the 1970s …

Importance In young febrile infants, serious bacterial infections (SBIs), including urinary tract
infections, bacteremia, and meningitis, may lead to dangerous complications. However …

Sepsis is a complex process defined as life-threatening organ dysfunction caused by a
dysregulated host response to infection. It is associated with significant morbidity and …

Importance Blood culture overuse in the pediatric intensive care unit (PICU) can lead to
unnecessary antibiotic use and contribute to antibiotic resistance. Optimizing blood culture …

Objective Acute pancreatitis (AP) is an inflammatory disease with rapid progression. In
severe cases, it can cause systemic inflammatory response syndrome (SIRS), multiple organ …

Children suffering from infectious diseases, both bacterial and viral, are often treated with
empirical antibiotics. Keeping in mind both the menace of microorganisms and antibiotic …

Procalcitonin (PCT) is useful for differentiating between viral and bacterial infections and for
reducing the unnecessary use of antibiotics. As the rise of antimicrobial resistance reaches …

OBJECTIVES: To assess the performance of the Yale Observation Scale (YOS) score and
unstructured clinician suspicion to identify febrile infants≤ 60 days of age with and without …